CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001034
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Citrate synthase 
Protein Synonyms/Alias
  
Gene Name
 gltA 
Gene Synonyms/Alias
 STM0730 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
418QLYTGYDKRDFKSALacetylation[1]
422GYDKRDFKSALKR**acetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 ACT_SITE 306 306 By similarity.
 ACT_SITE 363 363 By similarity.  
Keyword
 Allosteric enzyme; Complete proteome; Reference proteome; Transferase; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 427 AA 
Protein Sequence
MADTKAKITL TGDTTIELDV LKGTLGQDVI DIRSLGSKGV FTFDPGFTST ASCESKITFI 60
DGDEGILLHR GFPIDQLATD SNYLEVCYIL LYGEKPTQEE YDEFRTTVTR HTMIHEQITR 120
LFHAFRRDSH PMAVMCGITG ALAAFYHDSL DVNNPRHREI AAFRLLSKMP TMAAMCYKYS 180
IGQPFVYPRN DLSYAGNFLN MMFSTPCETY EVNPVLERAM DRILILHADH EQNASTSTVR 240
TAGSSGANPF ACIAAGIASL WGPAHGGANE AALKMLEEIS SVKHIPEFVR RAKDKNDSFR 300
LMGFGHRVYK NYDPRATVMR ETCHEVLKEL GTKDDLLEVA MELEHIALND PYFIEKKLYP 360
NVDFYSGIIL KAMGIPSSMF TVIFAMARTV GWIAHWNEMH TDGMKIARPR QLYTGYDKRD 420
FKSALKR 427 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004108; F:citrate (Si)-synthase activity; IEA:EC.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway. 
Interpro
 IPR016142; Citrate_synth-like_lrg_a-sub.
 IPR016143; Citrate_synth-like_sm_a-sub.
 IPR002020; Citrate_synthase-like.
 IPR016141; Citrate_synthase-like_core.
 IPR019810; Citrate_synthase_AS.
 IPR024176; Citrate_synthase_bac-typ.
 IPR010953; Citrate_synthase_typ-II. 
Pfam
 PF00285; Citrate_synt 
SMART
  
PROSITE
 PS00480; CITRATE_SYNTHASE 
PRINTS
 PR00143; CITRTSNTHASE.