UniProt Accession

 F8VP00_HUMAN; F8VP00 

Genbank Protein ID

 AC004801; AC074029 

Genbank Nucleotide ID

  

Protein Name

 6-phosphofructokinase, muscle type 

Protein Synonyms/Alias

  

Gene Name

 PFKM 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
60	DGFEGLAKGQIEEAG	ubiquitination	[1]
81	WTGQGGSKLGTKRTL	ubiquitination	[1, 2, 3]
91	TKRTLPKKSFEQISA	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 177 AA 

Protein Sequence

Gene Ontology

 GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
 GO:0003872; F:6-phosphofructokinase activity; IEA:InterPro.
 GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:InterPro. 

Interpro

 IPR022953; Phosphofructokinase.
 IPR000023; Phosphofructokinase_dom. 

Pfam

 PF00365; PFK 

SMART

  

PROSITE

  

PRINTS

 PR00476; PHFRCTKINASE.