CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027460
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 
Protein Synonyms/Alias
  
Gene Name
 PF14_0511 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
361KIYPALFKLFCNNSLacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 910 AA 
Protein Sequence
MDYENFVKSA EEINNLHNVN YLETKDLNDF NWKAAYYICK EIYDKQQINK DGYVVIGLSG 60
GRTPIDVYKN MCLIKDIKID KSKLIFFIID ERYKSDDHKF SNYNNIKFLF HNLNINEKEQ 120
LYKPDTTKSI VDCILDYNDK IKIMIEKYKK VDIAILGMGS DFHIASLFPN IFYNIYMNNY 180
QNNYIYNEKT LDFINNDQDN DNLKYLKEYV YFTTTNQFDV RKRITVSLNL LANASSKIFL 240
LNSKDKLDLW KNMLIKSYIE VNYNLYPATY LIDTSCTNEN VNINNNNNNN NKNKNNYCYS 300
NTTVISCGYE NYTKSIEEIY DSKYALSLYS NSLNKEELLT IIIFGCSGDL AKKKIYPALF 360
KLFCNNSLPK DLLIIGFART VQDFDTFFDK IVIYLKRCLL CYEDWSISKK KDLLNGFKNR 420
CRYFVGNYSS SESFENFNKY LTTIEEEEAK KKYYATCYKM NGSDYNISNN VAEDNISIDD 480
ENKTNEYFQM CTPKNCPDNV FSSNYNFPYV INRMLYLALP PHIFVSTLKN YKKNCLNSKG 540
TDKILLEKPF GNDLDSFKML SKQILENFNE QQIYRIDHYL GKDMVSGLLK LKFTNTFLLS 600
LMNRHFIKCI KITLKETKGV YGRGQYFDPY GIIRDVMQNH MLQLLTLITM EDPIDLNDES 660
VKNEKIKILK SIPSIKLEDT IIGQYEKAEN FKEDENNDDE SKKNHSYHDD PHIDKNSITP 720
TFCTCILYIN SINWYGVPII FKSGKGLNKD ICEIRIQFHN IMGSSDENMN NNEFVIILQP 780
VEAIYLKMMI KKTGCEEMEE VQLNLTVNEK NKKINVPEAY ETLLLECFKG HKKKFISDEE 840
LYESWRIFTP LLKELQEKQV KPLKYSFGSS GPKEVFGLVK KYYNYGKNYT HRPEFVRKSS 900
FYEDDLLDIN 910 
Gene Ontology
 GO:0017057; F:6-phosphogluconolactonase activity; ISS:GeneDB_Pfalciparum.
 GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:EC.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006098; P:pentose-phosphate shunt; TAS:GeneDB_Pfalciparum. 
Interpro
 IPR001282; G6P_DH.
 IPR022675; G6P_DH_C.
 IPR022674; G6P_DH_NAD-bd.
 IPR006148; Glc/Gal-6P_isomerase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02781; G6PD_C
 PF00479; G6PD_N
 PF01182; Glucosamine_iso 
SMART
  
PROSITE
  
PRINTS
 PR00079; G6PDHDRGNASE.