CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-037155
UniProt Accession
E7EVD1_HUMAN
;
E7EVD1
Genbank Protein ID
AL611942
Genbank Nucleotide ID
Protein Name
U4/U6 small nuclear ribonucleoprotein Prp3
Protein Synonyms/Alias
Gene Name
PRPF3
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
52
KKAADHL
K
PFLDDST
ubiquitination
[1]
Reference
[1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [
PMID: 21890473
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
634 AA
Protein Sequence
MALSKRELDE LKPWIEKTVK RVLGFSEPTV VTAALNCVGK GMDKKKAADH LKPFLDDSTL 60
RFVDKLFEAV EEGRSSRHSK SSSDRSRKRE LKIKQMMEAA TRQIEERKKQ LSFISPPTPQ 120
PKTPSSSQPE RLPIGNTIQP SQAATFMNDA IEKARKAAEL QARIQAQLAL KPGLIGNANM 180
VGLANLHAMG IAPPKVELKD QTKPTPLILD EQGRTVDATG KEIELTHRMP TLKANIRAVK 240
REQFKQQLKE KPSEDMESNT FFDPRVSIAP SQRQRRTFKF HDKGKFEKIA QRLRTKAQLE 300
KLQAEISQAA RKTGIHTSTR LALIAPKKEL KEGDIPEIEW WDSYIIPNGF DLTEENPKRE 360
DYFGITNLVE HPAQLNPPVD NDTPVTLGVY LTKKEQKKLR RQTRREAQKE LQEKVRLGLM 420
PPPEPKVRIS NLMRVLGTEA VQDPTKVEAH VRAQMAKRQK AHEEANAARK LTAEQRKVKK 480
IKKLKEDISQ GVHISVYRVR NLSNPAKKFK IEANAGQLYL TGVVVLHKDV NVVVVEGGPK 540
AQKKFKRLML HRIKWDEQTS NTKGDDDEES DEEAVKKTNK CVLVWEGTAK DRSFGEMKFK 600
QCPTENMARE HFKKHGAEHY WDLALSESVL ESTD 634
Gene Ontology
GO:0005737
; C:cytoplasm; IDA:HPA.
GO:0005634
; C:nucleus; IDA:HPA.
GO:0046540
; C:U4/U6 x U5 tri-snRNP complex; IEA:InterPro.
GO:0000398
; P:mRNA splicing, via spliceosome; IEA:InterPro.
Interpro
IPR010541
; DUF1115.
IPR013881
; Pre-mRNA_splic_Prp3.
IPR027104
; Prp3.
IPR002483
; PWI_dom.
Pfam
PF06544
; DUF1115
PF08572
; PRP3
PF01480
; PWI
SMART
SM00311
; PWI
PROSITE
PS51025
; PWI
PRINTS