UniProt Accession

 CWC15_RAT; Q5BJP2 

Genbank Protein ID

 BC091396 

Genbank Nucleotide ID

 AAH91396.1 

Protein Name

 Spliceosome-associated protein CWC15 homolog 

Protein Synonyms/Alias

  

Gene Name

 Cwc15 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
18	PARGGRGKGEGDLSQ	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylthreonine (By similarity).
 MOD_RES 24 24 Phosphoserine (By similarity).
 MOD_RES 110 110 Phosphothreonine (By similarity).
 MOD_RES 121 121 Phosphoserine (By similarity).  

Keyword

 Acetylation; Coiled coil; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Spliceosome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 229 AA 

Protein Sequence

Gene Ontology

 GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
 GO:0003723; F:RNA binding; ISS:UniProtKB.
 GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB. 

Interpro

 IPR006973; Cwf_Cwc_15. 

Pfam

 PF04889; Cwf_Cwc_15 

SMART

  

PROSITE

  

PRINTS