CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041199
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 PERQ amino acid-rich with GYF domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Gigyf2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1103KNNASLSKSVGVSNRubiquitination[1]
1120KKVEEEEKLLKLFQGacetylation[2]
1120KKVEEEEKLLKLFQGsuccinylation[2]
1123EEEEKLLKLFQGVNKubiquitination[1]
1185LGDTSEAKEFAKQFLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1285 AA 
Protein Sequence
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA LFLKDYKIPF 60
DLLEKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA VLRLTGRGGG GGTVVGAPRG 120
RSSSRGRGRG RGECGFYQRS FDEVEGVFGR GGGREMHRSQ SWEERGDRRF EKPGRKDVGR 180
PNFEESGPTS VGRKHEFIRS ESENWRIFRE EQNGEDEDGG WRLAGSRRDG ERWRPHSPGW 240
REHMERRRRF EFDFRDRDDE RGYRRVRSGS GSIDDDRDSL PEWCLEDAEE EMGTFDSSGA 300
FLSLKKVQKE PIPEEQEMDF RPVEEGEERS DSDSSHNEEA KEPDKTNRRE GEKTDRAGAE 360
ASEEVPQTSL SSARPGTPSD HQPQEATQFE RKDEPKAEQV EKAEEENRSE NSLSAKVPSR 420
GDETVPASQQ PSTPLPPDTA SPLLILSPPV PTPSSASRPV ETAAVEAPGM SSVSTEPDDE 480
EGLKHLEQQA EKMVAYLQDS ALDDERLTSK LQEHRAKGVS IPLMHEAMQK WYYKDPQGEI 540
QGPFNNQEMA EWFQAGYFTM SLLVKRACDE SFQPLGDIMK MWGRVPFSPG PAPPPHMGEL 600
DQERLTRQQE LTALYQMQHL QYQQFLIQQQ YAQVLAQQQK AALSSQQQQQ LALLLQQFQA 660
LKMRMSDQNI IPSVTRSVSV PDTGSIWELQ PAASQPAVWE GGSVWDLPLD TTAPGPSLEQ 720
LQQLEKAKAA KLEQERREAE MRAKREEEER KRQEELRRQQ EEILRRQQEE ERKRREEEEL 780
ARRKQEEALR RQREQEIALR RQREEEERQQ QEEALRRLEE RRREEEERRK QEELLRKQEE 840
EAAKWAREEE EAQRRLEENR LRMEEEAARL RHEEEERKRK ELELQRQKDL MRQRQQQQEA 900
LRRLQQQQQQ QQLAQMKLPS SSTWGQQSNT ATCQSQATLS LAEIQKLEEE RERQLREEQR 960
RQQRELMKAL QQQQQQQQQQ KLSGWGNVSK PAGTTKSLLE IQQEEARQMQ KQQQQQQQQQ 1020
QQHQQSNRAR NSTHSNLHTS LGNSVWGSIN TGPSNQWASE LVSSIWSNAD TKNSNMGFWD 1080
DAVKEVGPRN STNKNKNNAS LSKSVGVSNR QNKKVEEEEK LLKLFQGVNK AQDGFTQWCE 1140
QMLHALNTAN NLDVPTFVSF LKEVESPYEV HDYTRAYLGD TSEAKEFAKQ FLERRAKQKV 1200
NQQRQQQQQQ QQQQDSVWGM NHSTLHSVFQ TNQSNNQQSN FEAVQSGKKK KKQKMVRADP 1260
SLLGFSVNAS SERLNMGEIE TLDDY 1285 
Gene Ontology
 GO:0008344; P:adult locomotory behavior; IMP:MGI.
 GO:0044267; P:cellular protein metabolic process; IMP:MGI.
 GO:0007631; P:feeding behavior; IMP:MGI.
 GO:0048873; P:homeostasis of number of cells within a tissue; IMP:MGI.
 GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:MGI.
 GO:0031571; P:mitotic G1 DNA damage checkpoint; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0050881; P:musculoskeletal movement; IMP:MGI.
 GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI.
 GO:0021522; P:spinal cord motor neuron differentiation; IMP:MGI. 
Interpro
 IPR003169; GYF. 
Pfam
 PF02213; GYF 
SMART
 SM00444; GYF 
PROSITE
 PS50829; GYF 
PRINTS