CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037537
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serpin H1 
Protein Synonyms/Alias
  
Gene Name
 SERPINH1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39TAEKLSPKAATLAERubiquitination[1]
94ATTASQAKAVLSAEQubiquitination[1, 2, 3]
129TARNVTWKLGSRLYGubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 165 AA 
Protein Sequence
MRSLLLLSAF CLLEAALAAE VKKPAAAAAP GTAEKLSPKA ATLAERSAGL AFSLYQAMAK 60
DQAVENILVS PVVVASSLGL VSLGGKATTA SQAKAVLSAE QLRDEEVHAG LGELLRSLSN 120
STARNVTWKL GSRLYGPSSV SFADDFVRSS KQHYNCEHSK INFRD 165 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:HPA.
 GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
 GO:0032964; P:collagen biosynthetic process; IEA:Compara.
 GO:0030199; P:collagen fibril organization; IEA:Compara.
 GO:0051604; P:protein maturation; IEA:Compara. 
Interpro
 IPR023796; Serpin_dom.
 IPR000215; Serpin_fam. 
Pfam
 PF00079; Serpin 
SMART
  
PROSITE
  
PRINTS