| Tag | Content |
|---|
| CPLM ID | CPLM-005908 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutathione S-transferase theta-2 |
Protein Synonyms/Alias | GST 12-12; GST class-theta-2; Glutathione S-transferase 12; Glutathione S-transferase Yrs-Yrs |
Gene Name | Gstt2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 52 | FSQVNCLKKVPVLKD | acetylation | [1] | | 131 | GVQVPEEKVERNRNS | acetylation | [1] | | 149 | ALQRLEDKFLRDRAF | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols. Highest activity towards ethacrynic acid and cumene hydroperoxide. |
Sequence Annotation | DOMAIN 2 82 GST N-terminal.
DOMAIN 88 230 GST C-terminal.
REGION 53 54 Glutathione binding (By similarity).
REGION 66 67 Glutathione binding (By similarity).
BINDING 40 40 Glutathione (By similarity). |
Keyword | Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 244 AA |
Protein Sequence | MGLELYLDLL SQPSRAVYIF AKKNGIPFQL RTVDLLKGQH LSEQFSQVNC LKKVPVLKDG 60
SFVLTESTAI LIYLSSKYQV ADHWYPADLQ ARAQVHEYLG WHADNIRGTF GVLLWTKVLG 120
PLIGVQVPEE KVERNRNSMV LALQRLEDKF LRDRAFIAGQ QVTLADLMSL EELIQPVALG 180
CNLFEGRPQL TAWRERVEAF LGAELCQEAH NPIMSVLGQA AKKTLPVPPP EAHASMMLRI 240
ARIP 244 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |