CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031222
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ61383, highly similar to Serine/threonine-protein kinase 24 (EC 2.7.11.1) 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
245HSELHPMKVLFLIPKubiquitination[1]
252KVLFLIPKNNPPTLEubiquitination[2]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Kinase; Nucleotide-binding; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 450 AA 
Protein Sequence
MGRDQRAVAG PALRRWLLLG TVTVGFLAQS VLANLKADPE ELFTKLEKIG KGSFGEVFKG 60
IDNRTQKVVA IKIIDLEEAE DEIEDIQQEI TVLSQCDSPY VTKYYGSYLK DTKLWIIMEY 120
LGGGSALDLL EPGPLDETQI ATILREILKG LDYLHSEKKI HRDIKAANVL LSEHGEVKLA 180
DFGVAGQLTD TQIKRNTFVG TPFWMAPEVI KQSAYDSKAD IWSLGITAIE LARGEPPHSE 240
LHPMKVLFLI PKNNPPTLEG NYSKPLKEFV EACLNKEPSF RPTAKELLKH KFILRNAKKT 300
SYLTELIDRY KRWKAEQSHD DSSSEDSDAE TDGQASGGSD SGDWIFTIRE KDPKNLENGA 360
LQPSDLDRNK MKDIPKRPFS QCLSTIISPL FAELKEKSQA CGGNLGSIEE LRGAIYLAEE 420
ACPGISDTMV AQLVQRLQRY SLSGGGTSSH 450 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004672; F:protein kinase activity; IEA:InterPro. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM 
PRINTS