CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038879
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ribonuclease pancreatic beta-type 
Protein Synonyms/Alias
  
Gene Name
 Rnase1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
35SRESSADKFKRQHMDacetylation[1]
59TYCNQMMKRQGMTKGacetylation[1]
102NGRNNCHKSSSTLRIacetylation[1]
119CRLKGSSKYPNCDYTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Endonuclease; Hydrolase; Nuclease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 152 AA 
Protein Sequence
MDMEKYLFPF SLLILVLGWV QPSLGGESRE SSADKFKRQH MDTEGPSKSS PTYCNQMMKR 60
QGMTKGSCKP VNTFVHEPLE DVQAICSQGQ VTCKNGRNNC HKSSSTLRIT DCRLKGSSKY 120
PNCDYTTTDS QKHIIIACDG NPYVPVHFDA SV 152 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0004522; F:pancreatic ribonuclease activity; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR001427; RNaseA.
 IPR023411; RNaseA_AS.
 IPR023412; RNaseA_domain. 
Pfam
 PF00074; RnaseA 
SMART
 SM00092; RNAse_Pc 
PROSITE
 PS00127; RNASE_PANCREATIC 
PRINTS
 PR00794; RIBONUCLEASE.