CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024116
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neuronal-specific septin-3 
Protein Synonyms/Alias
  
Gene Name
 Sept3 
Gene Synonyms/Alias
 Sep3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
98SSWNREEKIPKTVEIubiquitination[1]
101NREEKIPKTVEIKAIubiquitination[1]
118VIEEGGVKMKLTVIDubiquitination[1]
155EQYEKFLKEEVNIARubiquitination[1]
226EFKQRVRKELEVNGIubiquitination[1]
268FAVVGSDKEYQVNGKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). 
Sequence Annotation
 NP_BIND 68 75 GTP (By similarity).
 NP_BIND 208 216 GTP (By similarity).
 BINDING 102 102 GTP (By similarity).
 BINDING 265 265 GTP; via amide nitrogen and carbonyl
 BINDING 280 280 GTP (By similarity).
 MOD_RES 91 91 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Cell cycle; Cell division; Cell junction; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Synapse. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 350 AA 
Protein Sequence
MSKGLPEART DAAMSELVPE PRPKPAVPMK PVSINSNLLG YIGIDTIIEQ MRKKTMKTGF 60
DFNIMVVGQS GLGKSTLVNT LFKSQVSRKA SSWNREEKIP KTVEIKAIGH VIEEGGVKMK 120
LTVIDTPGFG DQINNENCWE PIEKYINEQY EKFLKEEVNI ARKKRIPDTR VHCCLYFISP 180
TGHSLRPLDL EFMKHLSKVV NIIPVIAKAD TMTLEEKSEF KQRVRKELEV NGIEFYPQKE 240
FDEDLEDKTE NDKIRQESMP FAVVGSDKEY QVNGKRVLGR KTPWGIIEVE NLNHCEFALL 300
RDFVIRTHLQ DLKEVTHNIH YETYRAKRLN DNGGLPPVSV DTEESHDSNP 350 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0031105; C:septin complex; IEA:InterPro.
 GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW. 
Interpro
 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase.
 IPR016491; Septin.
 IPR008114; Septin3. 
Pfam
 PF00735; Septin 
SMART
  
PROSITE
  
PRINTS
 PR01741; SEPTIN3.