UniProt Accession

 H7C2S8_HUMAN; H7C2S8 

Genbank Protein ID

 AC004876 

Genbank Nucleotide ID

  

Protein Name

 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 

Protein Synonyms/Alias

  

Gene Name

 PLOD3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
70	DPDMAFCKSFRDKGI	ubiquitination	[1, 2]
75	FCKSFRDKGIFLHLS	ubiquitination	[2]
208	LNVALNHKGLDYEGG	ubiquitination	[1]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 264 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
 GO:0008475; F:procollagen-lysine 5-dioxygenase activity; IEA:InterPro. 

Interpro

 IPR005123; Oxoglu/Fe-dep_dioxygenase.
 IPR006620; Pro_4_hyd_alph.
 IPR001006; Procol_lys_dOase. 

Pfam

 PF03171; 2OG-FeII_Oxy 

SMART

 SM00702; P4Hc 

PROSITE

 PS51471; FE2OG_OXY
 PS01325; LYS_HYDROXYLASE 

PRINTS