UniProt Accession

 PGS2_MOUSE; P28654 

Genbank Protein ID

 X53929 

Genbank Nucleotide ID

 CAA37876.1 

Protein Name

 Decorin 

Protein Synonyms/Alias

 Bone proteoglycan II; PG-S2; PG40 

Gene Name

 Dcn 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
316	RAGHPSRKASYSAVS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May affect the rate of fibrils formation. 

Sequence Annotation

 REPEAT 68 88 LRR 1.
 REPEAT 89 112 LRR 2.
 REPEAT 113 136 LRR 3.
 REPEAT 137 157 LRR 4.
 REPEAT 158 181 LRR 5.
 REPEAT 182 207 LRR 6.
 REPEAT 208 228 LRR 7.
 REPEAT 229 252 LRR 8.
 REPEAT 253 276 LRR 9.
 REPEAT 277 299 LRR 10.
 REPEAT 300 329 LRR 11.
 REPEAT 330 354 LRR 12.
 CARBOHYD 34 34 O-linked (Xyl...) (glycosaminoglycan) (By
 CARBOHYD 206 206 N-linked (GlcNAc...) (Potential).
 CARBOHYD 241 241 N-linked (GlcNAc...) (Potential).
 CARBOHYD 257 257 N-linked (GlcNAc...) (Potential).
 CARBOHYD 298 298 N-linked (GlcNAc...) (Potential).
 DISULFID 49 55 By similarity.
 DISULFID 53 62 By similarity.
 DISULFID 308 341 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Extracellular matrix; Glycoprotein; Leucine-rich repeat; Proteoglycan; Reference proteome; Repeat; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 354 AA 

Protein Sequence

Gene Ontology

 GO:0005589; C:collagen type VI; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0050840; F:extracellular matrix binding; IDA:MGI.
 GO:0005539; F:glycosaminoglycan binding; IDA:MGI.
 GO:0007568; P:aging; IEA:Compara.
 GO:0001822; P:kidney development; IEA:Compara.
 GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IDA:MGI.
 GO:0001890; P:placenta development; IEA:Compara.
 GO:0032496; P:response to lipopolysaccharide; IEA:Compara.
 GO:0009612; P:response to mechanical stimulus; IEA:Compara.
 GO:0007519; P:skeletal muscle tissue development; IEA:Compara.
 GO:0042060; P:wound healing; IEA:Compara. 

Interpro

 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR000372; LRR-contain_N.
 IPR016352; SLRP_I_decor/aspor/byglycan. 

Pfam

 PF01462; LRRNT 

SMART

 SM00369; LRR_TYP
 SM00013; LRRNT 

PROSITE

 PS51450; LRR 

PRINTS