UniProt Accession

 ELF1_YEAST; P36053; D6VX39 

Genbank Protein ID

 Z26877; Z28160; AY558355; BK006944 

Genbank Nucleotide ID

 CAA81494.1; CAA82002.1; AAS56681.1; DAA09005.1 

Protein Name

 Transcription elongation factor 1 

Protein Synonyms/Alias

  

Gene Name

 ELF1 

Gene Synonyms/Alias

 YKL160W; YKL614 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
18	PTKRLVQKLDTKFNC	acetylation	[1]
22	LVQKLDTKFNCLFCN	ubiquitination	[2, 3]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. 

Sequence Annotation

 METAL 25 25 Zinc (By similarity).
 METAL 28 28 Zinc (By similarity).
 METAL 49 49 Zinc (By similarity).
 METAL 52 52 Zinc (By similarity).
 MOD_RES 55 55 Phosphoserine.
 MOD_RES 117 117 Phosphoserine.
 MOD_RES 124 124 Phosphoserine.
 MOD_RES 142 142 Phosphoserine.  

Keyword

 Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 145 AA 

Protein Sequence

Gene Ontology

 GO:0008023; C:transcription elongation factor complex; IDA:SGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0000993; F:RNA polymerase II core binding; IDA:SGD.
 GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.
 GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:SGD. 

Interpro

 IPR007808; Elf1. 

Pfam

 PF05129; Elf1 

SMART

  

PROSITE

  

PRINTS