| Tag | Content |
|---|
| CPLM ID | CPLM-018009 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rhophilin-1 |
Protein Synonyms/Alias | GTP-Rho-binding protein 1 |
Gene Name | RHPN1 |
Gene Synonyms/Alias | KIAA1929 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 475 | TLQRSLAKYAELDRE | ubiquitination | [1] | | 530 | PLSVFSAKNRWRLVG | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules (By similarity). |
Sequence Annotation | REPEAT 35 107 REM.
DOMAIN 108 482 BRO1.
DOMAIN 538 617 PDZ. |
Keyword | Alternative splicing; Complete proteome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 695 AA |
Protein Sequence | MILEERPDGA GAGEESPRLQ GCDSLTQIQC GQLQSRRAQI HQQIDKELQM RTGAENLYRA 60
TSNNRVRETV ALELSYVNSN LQLLKEELEE LSGGVDPGRH GSEAVTVPMI PLGLKETKEL 120
DWSTPLKELI SVHFGEDGAS YEAEIRELEA LRQAMRTPSR NESGLELLTA YYNQLCFLDA 180
RFLTPARSLG LFFHWYDSLT GVPAQQRALA FEKGSVLFNI GALHTQIGAR QDRSCTEGAR 240
RAMEAFQRAA GAFSLLRENF SHAPSPDMSA ASLCALEQLM MAQAQECVFE GLSPPASMAP 300
QDCLAQLRLA QEAAQVAAEY RLVHRTMAQP PVHDYVPVSW TALVHVKAEY FRSLAHYHVA 360
MALCDGSREC PPHLPMVLPR PPRAGSQPLC PPAATEGELP THEQVFLQPP TSSKPRGPVL 420
PQELEERRQL GKAHLKRAIL GQEEALRLHA LCRVLREVDL LRAVISQTLQ RSLAKYAELD 480
REDDFCEAAE APDIQPKTHQ KPEARMPRLS QGKGPDIFHR LGPLSVFSAK NRWRLVGPVH 540
LTRGEGGFGL TLRGDSPVLI AAVIPGSQAA AAGLKEGDYI VSVNGQPCRW WRHAEVVTEL 600
KAAGEAGASL QVVSLLPSSR LPSLGDRRPV LLGPRGLLRS QREHGCKTPA STWASPRPLL 660
NWSRKAQQGK TGGCPQPCAP VKPAPPSSLK HPGWP 695 |
Gene Ontology | GO:0005083; F:small GTPase regulator activity; IEA:Compara. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |