CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029650
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 TBC1 domain family member 22A 
Protein Synonyms/Alias
  
Gene Name
 TBC1D22A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
12GARKQFWKRSNSKLPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 458 AA 
Protein Sequence
MASDGARKQF WKRSNSKLPG SIQHVYGAQH PPFDPLLHGT LLRSTAKMPT TPVKAKRVST 60
FQEFESNTSD AWDAGEDDDE LLAMAAESLN SEVVMETANR VLRNHSQRQG RPTLQEGPGL 120
QQKPRPEAEP PSPPSGDLRL VKSVSESHTS CPAEELRRLS WSGIPKPVRP MTWKLLSGYL 180
PANVDRRPAT LQRKQKEYFA FIEHYYDSRN DEVHQDTYRQ IHIDIPRMSP EALILQPKVT 240
EIFERILFIW AIRHPASGYV QGINDLVTPF FVVFICEYIE AEEVDTVDVS GVPAEVLCNI 300
EADTYWCMSK LLDGIQDNYT FAQPGIQMKV KMLEELVSRI DEQVHRHLDQ HEVRYLQFAF 360
RWMNNLLMRE VPLRCTIRLW DTYQSEPDGF SHFHLYVCAA FLVRWRKEIL EEKDFQELLL 420
FLQNLPTAHW DDEDISLLLA EAYRLKFAFA DAPNHYKK 458 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
 GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. 
Interpro
 IPR000195; Rab-GTPase-TBC_dom. 
Pfam
 PF00566; RabGAP-TBC 
SMART
 SM00164; TBC 
PROSITE
 PS50086; TBC_RABGAP 
PRINTS