CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Iron-sulfur clusters transporter ATM1, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 ATM1 
Gene Synonyms/Alias
 MDY; YMR301C; YM9952.03C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
315VKYFNNEKYLADKYNacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. 
Sequence Annotation
 DOMAIN 111 401 ABC transmembrane type-1.
 DOMAIN 436 672 ABC transporter.
 NP_BIND 469 476 ATP (Potential).  
Keyword
 ATP-binding; Complete proteome; Ion transport; Iron; Iron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 690 AA 
Protein Sequence
MLLLPRCPVI GRIVRSKFRS GLIRNHSPVI FTVSKLSTQR PLLFNSAVNL WNQAQKDITH 60
KKSVEQFSSA PKVKTQVKKT SKAPTLSELK ILKDLFRYIW PKGNNKVRIR VLIALGLLIS 120
AKILNVQVPF FFKQTIDSMN IAWDDPTVAL PAAIGLTILC YGVARFGSVL FGELRNAVFA 180
KVAQNAIRTV SLQTFQHLMK LDLGWHLSRQ TGGLTRAMDR GTKGISQVLT AMVFHIIPIS 240
FEISVVCGIL TYQFGASFAA ITFSTMLLYS IFTIKTTAWR THFRRDANKA DNKAASVALD 300
SLINFEAVKY FNNEKYLADK YNGSLMNYRD SQIKVSQSLA FLNSGQNLIF TTALTAMMYM 360
GCTGVIGGNL TVGDLVLINQ LVFQLSVPLN FLGSVYRDLK QSLIDMETLF KLRKNEVKIK 420
NAERPLMLPE NVPYDITFEN VTFGYHPDRK ILKNASFTIP AGWKTAIVGS SGSGKSTILK 480
LVFRFYDPES GRILINGRDI KEYDIDALRK VIGVVPQDTP LFNDTIWENV KFGRIDATDE 540
EVITVVEKAQ LAPLIKKLPQ GFDTIVGERG LMISGGEKQR LAIARVLLKN ARIMFFDEAT 600
SALDTHTEQA LLRTIRDNFT SGSRTSVYIA HRLRTIADAD KIIVLDNGRV REEGKHLELL 660
AMPGSLYREL WTIQEDLDHL ENELKDQQEL 690 
Gene Ontology
 GO:0016021; C:integral to membrane; IBA:RefGenome.
 GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IMP:SGD.
 GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.
 GO:0006811; P:ion transport; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00664; ABC_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS