UniProt Accession

 BEX1_MACFA; Q2PG52 

Genbank Protein ID

 AB220385 

Genbank Nucleotide ID

 BAE72918.1 

Protein Name

 Protein BEX1 

Protein Synonyms/Alias

 Brain-expressed X-linked protein 1 homolog 

Gene Name

 BEX1 

Gene Synonyms/Alias

 QbsB-11523 

Created Date

 July 27, 2013 

Organism

 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) 

NCBI Taxa ID

 9541 

Lysine Modification

Position	Peptide	Type	References
102	LMEKLREKQLSHSLR	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity). 

Sequence Annotation

 MOD_RES 105 105 Phosphoserine (By similarity).  

Keyword

 Cytoplasm; Developmental protein; Differentiation; Neurogenesis; Nucleus; Phosphoprotein; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 128 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007399; P:nervous system development; IEA:UniProtKB-KW. 

Interpro

 IPR007623; BEX.
 IPR021156; TF_A-like/BEX-like. 

Pfam

 PF04538; BEX 

SMART

  

PROSITE

  

PRINTS