UniProt Accession

 E9QJW0_MOUSE; E9QJW0 

Genbank Protein ID

 AC121849; AC131766 

Genbank Nucleotide ID

  

Protein Name

 Microsomal glutathione S-transferase 1 

Protein Synonyms/Alias

  

Gene Name

 Mgst1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
116	AFQRITNKVFANPED	acetylation	[1]
116	AFQRITNKVFANPED	ubiquitination	[2]
129	EDCAGFGKGENAKKF	acetylation	[1]
129	EDCAGFGKGENAKKF	ubiquitination	[2]
134	FGKGENAKKFVRTDE	acetylation	[1]
134	FGKGENAKKFVRTDE	ubiquitination	[2]
142	KFVRTDEKVERVRRA	acetylation	[1, 3]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 229 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0004364; F:glutathione transferase activity; IDA:MGI.
 GO:0006749; P:glutathione metabolic process; IDA:MGI. 

Interpro

 IPR023352; MAPEG-like_dom.
 IPR001129; Membr-assoc_MAPEG. 

Pfam

 PF01124; MAPEG 

SMART

  

PROSITE

  

PRINTS