CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031181
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase 
Protein Synonyms/Alias
 cDNA FLJ50188, highly similar to Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichylmannosyltransferase (EC 2.4.1.-) 
Gene Name
 ALG3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
269SLLRDPSKRKVPPQPubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 382 AA 
Protein Sequence
MAAARLARAA PAAAGAALHA AGGRLPLPGG GGHHLLGHSQ GGMYPAGFVY IFMGLYYATS 60
RGTDIRMAQN IFAVLYLATL LLVFLIYHQT CKVPPFVFFF MCCASYRVHS IFVLRLFNDP 120
VAMVLLFLSI NLLLAQRWGW GCCFFSLAVS VKMNVLLFAP GLLFLLLTQF GFRGALPKLG 180
ICAGLQVVLG LPFLLENPSG YLSRSFDLGR QFLFHWTVNW RFLPEALFLH RAFHLALLTA 240
HLTLLLLFAL CRWHRTGESI LSLLRDPSKR KVPPQPLTPN QIVSTLFTSN FIGICFSRSL 300
HYQFYVWYFH TLPYLLWAMP ARWLTHLLRL LVLGLIELSW NTYPSTSCSS AALHICHAVI 360
LLQLWLGPQP FPKSTQHSKK AH 382 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. 
Interpro
 IPR007873; Glycosyltransferase_ALG3. 
Pfam
 PF05208; ALG3 
SMART
  
PROSITE
  
PRINTS