CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041737
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock 27kDa protein 1 
Protein Synonyms/Alias
 Heat shock protein beta-1 
Gene Name
 Hspb1 
Gene Synonyms/Alias
 rCG_21815 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
127GVVEITGKHEERQDEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 206 AA 
Protein Sequence
MTERRVPFSL LRSPSWEPFR DWYPAHSRLF DQAFGVPRFP DEWSQWFSSA GWPGYVRPLP 60
AATAEGPAAV TLAAPAFSRA LNRQLSSGVS EIRQTADRWR VSLDVNHFAP EELTVKTKEG 120
VVEITGKHEE RQDEHGYISR CFTRKYTLPP GVDPTLVSSS LSPEGTLTVE APLPKAVTQS 180
AEITIPVTFE ARAQIGGPES EQSGAK 206 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0030018; C:Z disc; IEA:Compara.
 GO:0008426; F:protein kinase C inhibitor activity; IEA:Compara.
 GO:0007243; P:intracellular protein kinase cascade; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0045766; P:positive regulation of angiogenesis; IEA:Compara.
 GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IEA:Compara.
 GO:0038033; P:positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; IEA:Compara.
 GO:0032731; P:positive regulation of interleukin-1 beta production; IEA:Compara.
 GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IEA:Compara.
 GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW.
 GO:0009615; P:response to virus; IEA:Compara. 
Interpro
 IPR002068; a-crystallin/Hsp20_dom.
 IPR001436; Alpha-crystallin/HSP.
 IPR008978; HSP20-like_chaperone. 
Pfam
 PF00011; HSP20 
SMART
  
PROSITE
 PS01031; HSP20 
PRINTS
 PR00299; ACRYSTALLIN.