CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011574
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable dipeptidyl peptidase 3 
Protein Synonyms/Alias
 Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase III; DPP III 
Gene Name
 YOL057W; O1232 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
38KYAHFMSKASHAGSRubiquitination[1]
632ECVKDYLKHLHVYKCacetylation[2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
  
Sequence Annotation
 ACT_SITE 461 461 By similarity.
 METAL 460 460 Zinc; catalytic (By similarity).
 METAL 465 465 Zinc; catalytic (By similarity).  
Keyword
 3D-structure; Aminopeptidase; Complete proteome; Cytoplasm; Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MSHFFADHDA PLSMLSVKTE YFPQLTDKEQ KYAHFMSKAS HAGSRVVMRQ VSHESEPIFD 60
LILAIHSKLN GKYPEDDITQ KQQTGLYLEY VSQFLSNLGN FKSFGDTKFI PRCEVKFFKQ 120
LLELAKINPC SSPLTLSPVD VNHEFTSHHL FSTINELIDI GIYHVEEKAA LLGFPSQGYT 180
SAYYLGLPVT PEDMALLKEQ LFAELAILPE NTRINKVGEN SFQIWVASEN VKNQITETYP 240
SGQITLSNAV TKVEFIFGDH SREMRLVASY LKEAQKFAAN DTQKAMLQEY INHFVTGSSQ 300
AHKEAQKLWV KDISPVIETN IGFIETYREP SGIIGEFESL VAIQNKERTA KFSSLVNNAE 360
EFISLLPWSK DYEKPIFNPP DFTSLEVLTF TGSGIPAGIN IPNYDDVRLK IGFKNVSLGN 420
ILSAAAKSSS KHPPSFISQE DRPIFEKYQS DSFEVQVGIH ELLGHGSGKL LTEFTDGFNF 480
DKENPPLGLD GKPVSTYYKV GETWGSKFGQ LAGPFEECRA EVIAMFLLTN KKILDIFGFH 540
DVESQDKVIY AGYLQMARAG LLALEYWNPK TGKWGQPHMQ ARFSIMKTFM KHSTDKNFLK 600
LEMNSTNDDF AIKLDKSLIK TAGHECVKDY LKHLHVYKCS GDVEQGSKYF IDRSTVTPDL 660
ASLRDIVLSK RLPRRQFIQS NSYIDDNNKV TLKEYDETPQ GMLQSFLDRE L 711 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
 GO:0008239; F:dipeptidyl-peptidase activity; IDA:SGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
 GO:0006508; P:proteolysis; ISS:SGD. 
Interpro
 IPR005317; Dipeptidyl-peptase3. 
Pfam
  
SMART
  
PROSITE
  
PRINTS