UniProt Accession

 B4DK71_HUMAN; B4DK71 

Genbank Protein ID

 AC098476; AK296421 

Genbank Nucleotide ID

 BAG59083.1 

Protein Name

 Phosphatidylinositide phosphatase SAC1 

Protein Synonyms/Alias

 cDNA FLJ55660, highly similar to Homo sapiens SAC1 suppressor of actin mutations 1-like (SACM1L), mRNA 

Gene Name

 SACM1L 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
189	IVHYNGSKASFVQTR	ubiquitination	[1, 2]
212	QRPNLKYKPLPQISK	ubiquitination	[2]
362	GVLHVGQKLEEQDEF	ubiquitination	[2]
386	DNANACAKQYAGTGA	ubiquitination	[2]
395	YAGTGALKTDFTRTG	ubiquitination	[2]
422	NSMIRYYKNNFSDGF	ubiquitination	[3]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 526 AA 

Protein Sequence

Gene Ontology

 GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. 

Interpro

 IPR002013; Syja_N. 

Pfam

 PF02383; Syja_N 

SMART

  

PROSITE

 PS50275; SAC 

PRINTS