CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025032
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Decapping enzyme, scavenger 
Protein Synonyms/Alias
 m7GpppX diphosphatase 
Gene Name
 Dcps 
Gene Synonyms/Alias
 rCG_22766 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
9ADTAPQLKRKREPEPacetylation[1]
126PRHLSDIKTTVVYPAacetylation[1]
136VVYPATEKHLQKYMRacetylation[1]
140ATEKHLQKYMRQDLRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 335 AA 
Protein Sequence
MADTAPQLKR KREPEPEEAE TPSTEKEAGV GNGTSAPVRL PFSGFRVQKV LRESARDKII 60
FLHGKVNEDS GDTHGEDAVV ILEKTPFQVE HVAQLLTGNP ELKLQFSNDI YSTYNLFPPR 120
HLSDIKTTVV YPATEKHLQK YMRQDLRLIR ETGDDYRSLT LPYLESQSLS IQWVYNILDK 180
KAEADRIVFE NPDPSDGFVL IPDLKWNQQQ LDDLYLIAIC HRRGIRSLRD LTPEHLPLLR 240
NILREGQEAI LKRYQVTGDR LRVYLHYLPS YYHLHVHFTA LGFEAPGSGV ERAHLLAEVI 300
ENLECDPKHY QRRTLTFALR TDDPLLQLLQ KAQQP 335 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0050072; F:m7G(5')pppN diphosphatase activity; IEA:Compara.
 GO:0000340; F:RNA 7-methylguanosine cap binding; IEA:Compara.
 GO:0036245; P:cellular response to menadione; IEA:Compara.
 GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
 GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:Compara.
 GO:0043069; P:negative regulation of programmed cell death; IEA:Compara. 
Interpro
 IPR008594; DcpS/DCS2.
 IPR019808; Histidine_triad_CS.
 IPR011146; HIT-like.
 IPR011145; Scavenger_mRNA_decap_enz_N. 
Pfam
 PF05652; DcpS 
SMART
  
PROSITE
 PS00892; HIT_1 
PRINTS