CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039012
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutathione reductase 
Protein Synonyms/Alias
  
Gene Name
 Gsr 
Gene Synonyms/Alias
 rCG_43149 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
25GFQNCKSKFNWHVIKacetylation[1]
32KFNWHVIKEKRDAYVacetylation[1]
153SLMIRHDKVLRSFDSacetylation[1]
184VLKFSQVKEVKKTPSacetylation[1]
234SKGLNLNKLGIQTDDacetylation[1]
322TEDEAVHKYGKDNVKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 410 AA 
Protein Sequence
MWNTAVHSEF IHDHVDYGFQ NCKSKFNWHV IKEKRDAYVS RLNNIYQNNL TKSHIEVIHG 60
YATFADGPQP TVEVNGKKFT APHILIATGG VPTVPHENQI PGASLGITSD GFFQLEDLPS 120
RSVIVGAGYI AVEIAGILSA LGSKTSLMIR HDKVLRSFDS LISSNCTEEL ENAGVEVLKF 180
SQVKEVKKTP SGLELHVVTA LPGRKPTVTT IPDVDCLLWA IGRDPNSKGL NLNKLGIQTD 240
DKGHILVDEF QNTNVKGVYA VGDVCGKALL TPVAIAAGRK LAHRLFEGKE DSRLDYDNIP 300
TVVFSHPPIG TVGLTEDEAV HKYGKDNVKI YSTAFTPMYH AVTTRKTKCV MKMVCANKEE 360
KVVGIHMQGI GCDEMLQGFA VAVKMGATKA DFDNTVAIHP TSSEELVTLR 410 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0004362; F:glutathione-disulfide reductase activity; IEA:Compara.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro.
 GO:0006749; P:glutathione metabolic process; IEA:InterPro. 
Interpro
 IPR016156; FAD/NAD-linked_Rdtase_dimer.
 IPR013027; FAD_pyr_nucl-diS_OxRdtase.
 IPR006322; Glutathione_Rdtase_euk/bac.
 IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
 IPR023753; Pyr_nucl-diS_OxRdtase_FAD/NAD.
 IPR001327; Pyr_OxRdtase_NAD-bd_dom. 
Pfam
 PF00070; Pyr_redox
 PF07992; Pyr_redox_2
 PF02852; Pyr_redox_dim 
SMART
  
PROSITE
  
PRINTS
 PR00368; FADPNR.