CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018496
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pleckstrin homology domain-containing family F member 2 
Protein Synonyms/Alias
 PH domain-containing family F member 2 
Gene Name
 Plekhf2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
44IGEGVLTKLCRKKPKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 35 131 PH.
 ZN_FING 152 212 FYVE-type.
 MOD_RES 44 44 N6-acetyllysine (By similarity).
 MOD_RES 239 239 Phosphoserine.
 MOD_RES 248 248 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 249 AA 
Protein Sequence
MVDRLANSEA NTRRISIVES CFGAAGQPLT IPGRVLIGEG VLTKLCRKKP KARQFFLFND 60
ILVYGNIVIQ KKKYNKQHII PLENVTIDSI KDEGELRNGW LIKTPTKSFA VYAATATEKS 120
EWMNHINKCV TDLLSKSGKT PSNEHAAVWV PDSEATVCMR CQKAKFTPVN RRHHCRKCGF 180
VVCGPCSEKR FLLPSQSSKP VRICDFCYDL LSTGDMAACQ PTRSDSYSQS LKSPLNDASD 240
DDDDDDSSD 249 
Gene Ontology
 GO:0030133; C:transport vesicle; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR000306; Znf_FYVE.
 IPR017455; Znf_FYVE-rel.
 IPR011011; Znf_FYVE_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF01363; FYVE
 PF00169; PH 
SMART
 SM00064; FYVE
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN
 PS50178; ZF_FYVE 
PRINTS