CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030540
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinetochore-associated protein 1 
Protein Synonyms/Alias
 cDNA FLJ36151 fis, clone TESTI2025365, highly similar to Kinetochore-associated protein 1 
Gene Name
 KNTC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
78KLKPKLLKLTQAKSSubiquitination[1]
83LLKLTQAKSSTLINKubiquitination[2, 3]
90KSSTLINKEITKITQubiquitination[2]
156SQDEKREKAEALLKKubiquitination[2]
227PDIHAAAKEIAEVNEubiquitination[2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 443 AA 
Protein Sequence
MLEHVITLPS AAQTRLPFHL IFFGTAQNFW KILSTELSEE SFPTLLLISK LMKFSLDTLY 60
VSTAKHVFEK KLKPKLLKLT QAKSSTLINK EITKITQTIE SCLLSIVNPE WAVAIAISLA 120
QDIPEGSFKI SALKFCLYLA ERWLQNIPSQ DEKREKAEAL LKKLHIQYRR SGTEAVLIAH 180
KLNTEEYLRV IGKPAHLIVS LYEHPSINQR IQNSSGTDYP DIHAAAKEIA EVNEINLEKV 240
WDMLLEKWLC PSTKPGEKPS ELFELQEDEA LRRVQYLLLS RPIDYSSRML FVFATSTTTT 300
LGMHQLTFAH RTRALQCLFY LADKETIESL FKKPIEEVKS YLRCITFLAS FETLNIPITY 360
ELFCSSPKEG MIKGLWKNHS HESMAVRLVT ELCLEYKIYD LQLWNGLLQK LLGFNMIPYL 420
RKVLKAISSI HSLWQRWRSC YVA 443 
Gene Ontology
  
Interpro
 IPR019527; RZZ-complex_KNTC1/ROD_C. 
Pfam
 PF10493; Rod_C 
SMART
  
PROSITE
  
PRINTS