CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026514
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0136 protein 
Protein Synonyms/Alias
  
Gene Name
 Morc3 
Gene Synonyms/Alias
 mKIAA0136; Zcwcc3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
936YVDGESLKLRSLRVNubiquitination[1, 2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
 Mathew R, Seiler MP, Scanlon ST, Mao AP, Constantinides MG, Bertozzi-Villa C, Singer JD, Bendelac A.
 Nature. 2012 Nov 22;491(7425):618-21. [PMID: 23086144] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 984 AA 
Protein Sequence
VGVAWCCRFR PGSGRGVEAR GGLVASQSGC GRGRSWLCSS LKMAAQPPTG IRLSALCPKF 60
LHTNSTSHTW PFSAVAELID NAYDPDVNAK QIWIDKTVIS DHICLTFTDN GNGMTADKLH 120
KMLSFGFSDK VTMNGHVPVG LYGNGFKSGS MRLGKDAMVF TKNGETMSVG FLSQTYLEVI 180
KAEHVVVPIV TFNKHRQMIN LTESKASLAA ILEHSLFSTE QKLLAELNAI MGKKGTRIII 240
WNLRSYKNAT EFDFEKDKYD IRIPEDLDET AGRKGYKKQE RMDQIAPESD YSLRAYCSIL 300
YLKPRMQIII RGQKVKTQLV SKSLAYIERD VYRPKFLTRT VRITFGFNCR NKDHYGIMMY 360
HKNRLIKAYE KVGCQLKANN MGVGVVGIIE CNFLKPTHNK QDFDYTNEYR LTILALGEKL 420
NDYWNEMKVK KNAEYPVNLP VEDIQKRPDQ TWVQCDACLK WRKLPDGIDQ LPEKWYCSNN 480
PDPQFRNCEV PEEPEDEDLV HPTYEKTYKK TSKERFRIRQ PEILPRILPQ INPELLYQTS 540
VSSQSFSPVK ESVPRPHLSE VTSPFAARII NLNLASPASE PENSSMKRKL GVHSSILNAK 600
TRRLSNPPVE NSSYKNDDDE DVIILEENST PKPAVDLEVK SDIEVKSEQS HTEQSGIHVD 660
LVSSPKPCVQ ASSTSTSTSR SDPGITVSTQ TDAPGLTVKK EESMEEDMGV RNGTATLSCV 720
GTEAKVQETS AESVDATSHQ LQELRSELLV VTQERDDYKR QCQMFTDQIQ VLQQRLLEMN 780
DKCVKKEKCH QSTETDAVFL LDSVNGQAES LDHLGSQYQQ ALQEIERLKR QCSALQQVKS 840
ECSQASCTES KSEVDEMAVQ LDDVFRQLDK CTIERDQYKN EVQLLEIEKS HIHSQCEELQ 900
TEVEQLKSTG QQAAADGSTA SNAEEPVSYV DGESLKLRSL RVNVGQLLAM IVPDLDLQQV 960
NYDVDVVDEI LGQVVEQMSE ISST 984 
Gene Ontology
 GO:0016235; C:aggresome; IEA:Compara.
 GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara.
 GO:0016605; C:PML body; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007569; P:cell aging; ISO:MGI.
 GO:0051457; P:maintenance of protein location in nucleus; ISO:MGI.
 GO:0048147; P:negative regulation of fibroblast proliferation; ISO:MGI.
 GO:0018105; P:peptidyl-serine phosphorylation; ISO:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI.
 GO:0050821; P:protein stabilization; ISO:MGI. 
Interpro
 IPR003594; HATPase_ATP-bd.
 IPR011124; Znf_CW. 
Pfam
 PF07496; zf-CW 
SMART
  
PROSITE
 PS51050; ZF_CW 
PRINTS