CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030085
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cryptochrome 2 (Photolyase-like) 
Protein Synonyms/Alias
 Cryptochrome 2 (Photolyase-like), isoform CRA_a; Cryptochrome-2 
Gene Name
 Cry2 
Gene Synonyms/Alias
 rCG_26511 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
474NAPESVQKAAKCIIGubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 594 AA 
Protein Sequence
MAAAAVVAAT VPAQSMGADG ASSVHWFRKG LRLHDNPALL AAVRGARCVR CVYILDPWFA 60
ASSSVGINRW RFLLQSLEDL DTSLRKLNSR LFVVRGQPAD VFPRLFKEWG VTRLTFEYDS 120
EPFGKERDAA IMKMAKEAGV EVVTENSHTL YDLDRIIELN GQKPPLTYKR FQALISRMEL 180
PKKPVGAVSS QHMENCRAEI QENHDDTYGV PSLEELGFPT EGLGPAVWQG GETEALARLD 240
KHLERKAWVA NYERPRMNAN SLLASPTGLS PYLRFGCLSC RLFYYRLWDL YRKVKRNSTP 300
PLSLFGQLLW REFFYTAATN NPRFDRMEGN PICIQIPWDR NPEALAKWAE GKTGFPWIDA 360
IMTQLRQEGW IHHLARHAVA CFLTRGDLWV SWESGVRVFD ELLLDADFSV NAGSWMWLSC 420
SAFFQQFFHC YCPVGFGRRT DPSGDYIRRY LPKLKGFPSR YIYEPWNAPE SVQKAAKCII 480
GVDYPRPIVN HAETSRLNIE RMKQIYQQLS RYRGLCLLAS VPSCVEDLSH PVAEPGSSQA 540
GSISNTGPRP LSSGPASPKR KLEAAEEPPG EELSKRARVT VTQMPAQEPP SKDS 594 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003684; F:damaged DNA binding; IEA:Compara.
 GO:0003913; F:DNA photolyase activity; IEA:InterPro.
 GO:0000988; F:protein binding transcription factor activity; IEA:Compara.
 GO:0003697; F:single-stranded DNA binding; IEA:Compara.
 GO:0007623; P:circadian rhythm; IEA:Compara.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0032515; P:negative regulation of phosphoprotein phosphatase activity; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006606; P:protein import into nucleus; IEA:Compara.
 GO:0042752; P:regulation of circadian rhythm; IEA:Compara.
 GO:2000118; P:regulation of sodium-dependent phosphate transport; IEA:Compara. 
Interpro
 IPR006050; DNA_photolyase_N.
 IPR005101; Photolyase_FAD-bd/Cryptochr_C.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00875; DNA_photolyase
 PF03441; FAD_binding_7 
SMART
  
PROSITE
 PS51645; PHR_CRY_ALPHA_BETA 
PRINTS