| Tag | Content |
|---|
| CPLM ID | CPLM-003674 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and sterile alpha motif domain-containing protein 1B |
Protein Synonyms/Alias | Amyloid-beta protein intracellular domain-associated protein 1; AIDA-1; E2A-PBX1-associated protein; EB-1 |
Gene Name | Anks1b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1122 | KFIDAANKNIIAEHE | ubiquitination | [1] | | 1248 | VEPGQEAKRGINTKY | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. |
Sequence Annotation | REPEAT 2 31 ANK 1.
REPEAT 58 87 ANK 2.
REPEAT 91 120 ANK 3.
REPEAT 127 156 ANK 4.
REPEAT 160 189 ANK 5.
REPEAT 193 222 ANK 6.
REPEAT 225 254 ANK 7.
DOMAIN 810 876 SAM 1.
DOMAIN 884 949 SAM 2.
DOMAIN 1056 1213 PID.
MOTIF 935 938 Nuclear localization signal (By
MOD_RES 901 901 Phosphotyrosine (By similarity). |
Keyword | Alternative splicing; ANK repeat; Cell junction; Cell membrane; Cell projection; Complete proteome; Cytoplasm; Membrane; Nucleus; Phosphoprotein; Postsynaptic cell membrane; Reference proteome; Repeat; Synapse. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1260 AA |
Protein Sequence | MGKDQELLEA ARTGNVALVE KLLSGRKGGI LGGGSGPLPL SNLLSIWRGP NVNCTDSSGY 60
TALHHAALNG HKDIVLKLLQ FEASTNVADN KGYFPIHLAA WKGDVEIVKI LIHHGPSHSR 120
VNEQNNENET ALHCAAQYGH SEVVAVLLEE LTDPTIRNSK LETPLDLAAL YGRLRVVKMI 180
ISAHPNLMSC NTRKHTPLHL AARNGHKAVV QVLLEAGMDV SCQTEKGSAL HEAALFGKVD 240
VVRVLLETGI DANIKDSLGR TVLDILKEHP SQKSLQIATL LQDYLEGVGR SVVLEEEHAQ 300
EDTAQETRLS SPAQSPSQKT KSETVTGELS KLLDEIKLCQ EKDYSFEDLC HTISDHYLDN 360
LSKISEEELG KNGSQSVRTS STINLSPGEV EDEEEDPNSC GPTGLWEALT PCNGCRNLGF 420
PMLAQESYPK KRNYPMEIVP SASLDTFPSE NENFLCELVD TAVTKKPCSL EIARAPSPRT 480
DNASEVAITA PGTGHHRNSS TGPTPDCSPP SPDTALKNIV KVIRPQPKQR TSIVSSLDFQ 540
RMNHNQEYFE ISTSTGCTSF TSSPPVSPPT SSVETTEIKN EGAEHTDDLS QQEDDEPPKE 600
YDAGQFAGLL HGSSPACEAP ENPFHLYGKR NQGEDGQEEA SLANSPLPFK QTPIENNPEP 660
SVKKIKPKVV SRTIFHKRSH QLENHTIVGT RMSRGGSRNG DQWGVNPGGF VERACTLGRI 720
RSLPKALIDM HLSKNVSKSD SDLIAYPSKD KARVNWSKSS TAERSSKDNS ERTPSFTSEW 780
EEIDKIMNSI DVGINSELEG MNGEATRPRC PVQTVGQWLE SIGLPQYENH LTANGFDNVQ 840
FMGSNVMEDQ DLLEIGILNS GHRQRILQAI QLLPKMRPIG HDGYHPTSVA EWLDSIELGD 900
YTKAFLINGY TSMDLLKKIW ELELINVLKI SLIGHRKRIL ASLGDRLHED PPQKPPRSIT 960
LREPSGNHTP PQLSPSLSQS TYTTGGSLDV PHIIMQGDAR RRRNENYFDD IPRSKLERQM 1020
AQTGDWGEPS ITLRPPNEAT ASTPVQYWQH HPEKLIFQSC DYKAFYLGSM LIKELRGTES 1080
TQDACAKMRA NCQKSTEQMK KVPTIILSVS YKGVKFIDAA NKNIIAEHEI RNISCAAQDP 1140
EDLSTFAYIT KDLKSNHHYC HVFTAFDVNL AYEIILTLGQ AFEVAYQLAL QARKGGHSST 1200
LPESFENKPS KPIPKPRVSI RKSVQIDPSE QKTLANLPWI VEPGQEAKRG INTKYETTIF 1260 |
Gene Ontology | GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell. GO:0030054; C:cell junction; IEA:UniProtKB-KW. GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell. GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |