CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041741
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Citrate synthase 
Protein Synonyms/Alias
  
Gene Name
 Cs 
Gene Synonyms/Alias
 rCG_42519 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
43ILSNLIPKEQARVKTacetylation[1]
76YGGMRGMKGLVYETSacetylation[1]
103YSIPECQKLLPKAKGacetylation[1]
215KLPCVAAKIYRNLYRacetylation[1]
321QLQKEVGKDVSDEKLacetylation[1]
327GKDVSDEKLRDYIWNacetylation[1]
366CQREFALKHLPKDPMacetylation[1]
370FALKHLPKDPMFKLVacetylation[1]
375LPKDPMFKLVAQLYKacetylation[1]
382KLVAQLYKIVPNILLacetylation[1]
393NILLEQGKAKNPWPNacetylation[1]
450GFPLERPKSMSTDGLacetylation[1]
459MSTDGLMKFVDSKSGacetylation[1]
464LMKFVDSKSG*****acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 466 AA 
Protein Sequence
MALLTAAARL LGAKNSSCLV LAARHASASS TNLKDILSNL IPKEQARVKT FRQQHGKTVV 60
GQITVDMMYG GMRGMKGLVY ETSVLDPDEG IRFRGYSIPE CQKLLPKAKG GEEPLPEGLF 120
WLLVTGQMPT EEQVSWLSQE WAKRAALPSH VVTMLDNFPT NLHPMSQLSA AITALNSESN 180
FARAYAEGIN RTKYWELIYE DCMDLIAKLP CVAAKIYRNL YREGSSIGAI DSKLDWSHNF 240
TNMLGYTEPQ FTELMRLYLT IHSDHEGGNV SAHTSHLVGS ALSDPYLSFA AAMNGLAGPL 300
HGLANQEVLV WLTQLQKEVG KDVSDEKLRD YIWNTLNSGR VVPGYGHAVL RKTDPRYSCQ 360
REFALKHLPK DPMFKLVAQL YKIVPNILLE QGKAKNPWPN VDAHSGVLLQ YYGMTEMNYY 420
TVLFGVSRAL GVLAQLIWSR ALGFPLERPK SMSTDGLMKF VDSKSG 466 
Gene Ontology
 GO:0005759; C:mitochondrial matrix; IEA:Compara.
 GO:0004108; F:citrate (Si)-synthase activity; IEA:Compara.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro. 
Interpro
 IPR016142; Citrate_synth-like_lrg_a-sub.
 IPR002020; Citrate_synthase-like.
 IPR016141; Citrate_synthase-like_core.
 IPR019810; Citrate_synthase_AS.
 IPR010109; Citrate_synthase_euk. 
Pfam
 PF00285; Citrate_synt 
SMART
  
PROSITE
 PS00480; CITRATE_SYNTHASE 
PRINTS
 PR00143; CITRTSNTHASE.