CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027512
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Histidyl-tRNA synthetase, isoform D 
Protein Synonyms/Alias
  
Gene Name
 Aats-his 
Gene Synonyms/Alias
 CG6335; Dmel_CG6335 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
501VKAEHSYKLNPKLLVacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 564 AA 
Protein Sequence
MSDTREQILE QIKVQGDLVR QLKAAKESKE KTAPSGGGRV SSSGVPAQRQ QQQQPQKQQQ 60
AQVQQQQHEQ LHQIDEEVAR LLALKATLGG DAAPTNQKFT LKTPKGTRDY GPQQMTLRQG 120
VLDKIVQVFK RHGGEAIDTP VFELKEVLTG KYGEDSKLIY DLKDQGGEIL SMRYDLTVPL 180
ARYLAMNKIS SIKRYHIAKV YRRDNPAMTK GRYREFYQCD FDIAGTYDPM LPDAECVKIV 240
SEILDTLDIG DYVIKLNHRQ LLDGMFQACG VPADSFRTIC SAVDKLDKSP WADVRKEMVD 300
EKGLDEAAAD RIGEYVRLSG GAELVEQLLA NEKLKAVPNA VKGLEGMKQL LKYCSIFGLD 360
KRVSFDLSLA RGLDYYTGVI YEGVLKGESA TVASPAKTSQ QNGEQANEPA TVGSVAGGGR 420
YDNLVGMFDP RGKAVPCVGV SIGVERIFSV LEARAAASGL KLRTSDVEVY VASAHKGLHE 480
QRLKVLNLLW DAGVKAEHSY KLNPKLLVQL QHCEEHQIPL VVVLGDAELA QGLVKLREVT 540
TREETNVKLE DLAAEIRRRQ QASA 564 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
 GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro. 
Interpro
 IPR006195; aa-tRNA-synth_II.
 IPR004154; Anticodon-bd.
 IPR004516; HisRS/HisZ.
 IPR009068; S15_NS1_RNA-bd.
 IPR000738; WHEP-TRS. 
Pfam
 PF03129; HGTP_anticodon 
SMART
 SM00991; WHEP-TRS 
PROSITE
 PS50862; AA_TRNA_LIGASE_II
 PS51185; WHEP_TRS_2 
PRINTS