UniProt Accession

 FABD_MOUSE; Q8R3F5; Q4FZH0 

Genbank Protein ID

 BC099494; BC025519 

Genbank Nucleotide ID

 AAH99494.1; AAH25519.1 

Protein Name

 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial 

Protein Synonyms/Alias

 MCT; Mitochondrial malonyltransferase; [Acyl-carrier-protein] malonyltransferase 

Gene Name

 Mcat 

Gene Synonyms/Alias

 Mt 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
312	THPQHIRKLLGQQVV	acetylation	[1]
312	THPQHIRKLLGQQVV	succinylation	[1]
323	QQVVSPVKWEQTMHS	acetylation	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias (By similarity). 

Sequence Annotation

 ACT_SITE 151 151 By similarity.
 ACT_SITE 268 268 By similarity.  

Keyword

 Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Mitochondrion; Reference proteome; Transferase; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 381 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IEA:EC.
 GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway. 

Interpro

 IPR001227; Ac_transferase_dom.
 IPR014043; Acyl_transferase.
 IPR016035; Acyl_Trfase/lysoPLipase.
 IPR016036; Malonyl_transacylase_ACP-bd. 

Pfam

 PF00698; Acyl_transf_1 

SMART

  

PROSITE

  

PRINTS