CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017765
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycerate kinase 
Protein Synonyms/Alias
  
Gene Name
 Glyctk 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
126AMEHAGKKEMLLKPHubiquitination[1]
131GKKEMLLKPHSRVQVacetylation[2]
200EEKQMLTKLLAARGAacetylation[2, 3]
200EEKQMLTKLLAARGAubiquitination[1]
285AALPRSVKTVLSRADubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 523 AA 
Protein Sequence
MAAALQVLPC LLRAPSRPLL WGPPVARMTS GMALAEQARQ LFDSAVGAVQ PGPMLQRTLS 60
LDPSGRQLKV RDRTFQLREN LYLVGFGKAV LGMAAAAEEL LAQHLVQGVI SVPKGIRAAM 120
EHAGKKEMLL KPHSRVQVFE GAEDNLPDRD ALRAALTIQQ LAEGLTADDL LLVLISGGGS 180
ALLPAPIPPV TLEEKQMLTK LLAARGATIQ ELNTIRKALS QLKGGGLAQA AYPAQVISLI 240
LSDVIGDPLE VIASGPTVAS AHSVQDCLHI LNHYGLRAAL PRSVKTVLSR ADSDPHGPHT 300
CGHVLNVIIG SNSLALAEAQ RQAEVLGYHA MVLSTAMQGD VKRVARFYGL LARVAAAHLT 360
PSLAERPLEE EAELHQLAAE LQLPDLQLEE ALEAVAKAKG PVCLLAGGEP TVQLQGSGKG 420
GRNQELALHV GVELGRQPLG PIDVLFLSGG TDGQDGPTKV AGAWVMSDLI SQASAESLDI 480
ATSLTNNDSY TFFCRFRGGT HLLHTGLTGT NVMDVHLLIL HPQ 523 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008887; F:glycerate kinase activity; ISS:UniProtKB.
 GO:0006468; P:protein phosphorylation; ISS:UniProtKB. 
Interpro
 IPR025286; DUF4147.
 IPR007835; MOFRL. 
Pfam
 PF13660; DUF4147
 PF05161; MOFRL 
SMART
  
PROSITE
  
PRINTS