CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008554
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleoporin NUP84 
Protein Synonyms/Alias
 Nuclear pore protein NUP84 
Gene Name
 NUP84 
Gene Synonyms/Alias
 YDL116W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
20TKFSDTLKEFKIEQNubiquitination[1]
382ASNDIIDKPYLLRIVubiquitination[1]
676KKLVEAAKLLKIPKFubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP84 is involved in nuclear poly(A)+ RNA export, in NPC assembly and distribution, as well as in nuclear envelope organization. 
Sequence Annotation
  
Keyword
 3D-structure; Coiled coil; Complete proteome; Membrane; mRNA transport; Nuclear pore complex; Nucleus; Protein transport; Reference proteome; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 726 AA 
Protein Sequence
MELSPTYQTE RFTKFSDTLK EFKIEQNNEQ NPIDPFNIIR EFRSAAGQLA LDLANSGDES 60
NVISSKDWEL EARFWHLVEL LLVFRNADLD LDEMELHPYN SRGLFEKKLM QDNKQLYQIW 120
IVMVWLKENT YVMERPKNVP TSKWLNSITS GGLKSCDLDF PLRENTNVLD VKDKEEDHIF 180
FKYIYELILA GAIDEALEEA KLSDNISICM ILCGIQEYLN PVIDTQIANE FNTQQGIKKH 240
SLWRRTVYSL SQQAGLDPYE RAIYSYLSGA IPNQEVLQYS DWESDLHIHL NQILQTEIEN 300
YLLENNQVGT DELILPLPSH ALTVQEVLNR VASRHPSESE HPIRVLMASV ILDSLPSVIH 360
SSVEMLLDVV KGTEASNDII DKPYLLRIVT HLAICLDIIN PGSVEEVDKS KLITTYISLL 420
KLQGLYENIP IYATFLNESD CLEACSFILS SLEDPQVRKK QIETINFLRL PASNILRRTT 480
QRVFDETEQE YSPSNEISIS FDVNNIDMHL IYGVEWLIEG KLYVDAVHSI IALSRRFLLN 540
GRVKALEQFM ERNNIGEICK NYELEKIADN ISKDENEDQF LEEITQYEHL IKGIREYEEW 600
QKSVSLLSSE SNIPTLIEKL QGFSKDTFEL IKTFLVDLTS SNFADSADYE ILYEIRALYT 660
PFLLMELHKK LVEAAKLLKI PKFISEALAF TSLVANENDK IYLLFQSSGK LKEYLDLVAR 720
TATLSN 726 
Gene Ontology
 GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
 GO:0031080; C:nuclear pore outer ring; IDA:SGD.
 GO:0017056; F:structural constituent of nuclear pore; IMP:SGD.
 GO:0030466; P:chromatin silencing at silent mating-type cassette; IDA:SGD.
 GO:0006302; P:double-strand break repair; IMP:SGD.
 GO:0035392; P:maintenance of chromatin silencing at telomere; IMP:SGD.
 GO:0031990; P:mRNA export from nucleus in response to heat stress; IMP:SGD.
 GO:0031081; P:nuclear pore distribution; IMP:SGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
 GO:0000973; P:posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.
 GO:0006606; P:protein import into nucleus; IMP:SGD.
 GO:0034398; P:telomere tethering at nuclear periphery; IMP:SGD. 
Interpro
 IPR007252; Nup84_Nup100. 
Pfam
 PF04121; Nup84_Nup100 
SMART
  
PROSITE
  
PRINTS