CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040394
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 POU domain, class 6, transcription factor 2 
Protein Synonyms/Alias
  
Gene Name
 Pou6f2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
435EEIREFAKAFKIRRLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 637 AA 
Protein Sequence
XGARGNTVLP DPGTPDQHQA CQTHPTFPVG PQPLLTAQQL ASAVAGVMPG GPPALNQPIL 60
IPFNMAGQLG GQQGLVLTLP TANLTNIQGL VAAAAAGGIM TLPLQNLQAT SSLNSQLQQL 120
QQLQLQQQQQ QQQQQQQQQQ QQQQPPPPPT SQHPQPASQA PPQSQPTPPH QPPPASQQLP 180
APPAQLQQAT QPQQHQPHSH PQNQTQNQPS PTQQSSSPPQ KPSPSPGHSL PSPLTPPNPL 240
QLVNNPLASQ AAAAAAAMGS IASSQAFGNA LSSLQGVTGQ LVTNAQGQII GTIPLMPNPG 300
PSSQAASGTQ GLQVQPITPQ LLTNAQGQII ATVIGNQILP VINTQGITLS PIKPGQQLHQ 360
SSQTSVGQAG TQGNLLHLAH GQAATSHSPV RQASSSSSSS SSSSALSVGQ LVSNPQTAAG 420
EVDGVNLEEI REFAKAFKIR RLSLGLTQTQ VGQALSATEG PAYSQSAICR HTILRSHFFL 480
PQEAQENTIA SSLTAKLNPG LLYPARFEKL DITPKSAQKI KPVLERWMAE AEARHRAGMQ 540
NLTEFIGSEP SKKRKRRTSF TPQALEILNA HFEKNTHPSG QEMTEIAEKL NYDREVVRVW 600
FCNKRQALKN TIKRLKQHEP TSAAPLEPLA DSPEENC 637 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. 
Interpro
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR010982; Lambda_DNA-bd_dom.
 IPR013847; POU.
 IPR000327; POU_specific. 
Pfam
 PF00046; Homeobox
 PF00157; Pou 
SMART
 SM00389; HOX
 SM00352; POU 
PROSITE
 PS50071; HOMEOBOX_2
 PS00035; POU_1
 PS00465; POU_2
 PS51179; POU_3 
PRINTS
 PR00028; POUDOMAIN.