CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020478
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glyoxalase domain-containing protein 4 
Protein Synonyms/Alias
  
Gene Name
 Glod4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
124TEAPGGYKFYLQDRSubiquitination[1]
140SQSDPVLKVTLAVSDubiquitination[1]
170IYEQDEEKQRALLGYacetylation[2]
273KMDPKGSKLLDDAMEacetylation[3]
273KMDPKGSKLLDDAMEsuccinylation[3]
283DDAMEADKSDEWFATubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Mitochondrion; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
MATRRALHFV FKVKNRFQTV HFFRDVLGMQ VLRHEEFEEG CKAACNGPYD GKWSKTMVGF 60
GPEDDHFVAE LTYNYGIGDY KLGNDFMGIT LASSQAVSNA RKLEWPLSKV AEGIFETEAP 120
GGYKFYLQDR SPSQSDPVLK VTLAVSDLQK SLNYWSNLLG MKIYEQDEEK QRALLGYADN 180
QCKLELQGIQ GAVDHAAAFG RIAFSCPQKE LPDLEDLMKR ESHSILTPLV SLDTPGKATV 240
QVVILADPDG HEICFVGDEA FRELSKMDPK GSKLLDDAME ADKSDEWFAT RNKPKASG 298 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI. 
Interpro
 IPR025870; Glyoxalase-like_dom. 
Pfam
 PF12681; Glyoxalase_2 
SMART
  
PROSITE
  
PRINTS