UniProt Accession

 D3YX62_MOUSE; D3YX62 

Genbank Protein ID

 AC166903 

Genbank Nucleotide ID

  

Protein Name

 Heme oxygenase 2 

Protein Synonyms/Alias

  

Gene Name

 Hmox2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
37	ADLSELLKEGTKEAH	acetylation	[1]
198	VDNAQQFKQFYRARM	ubiquitination	[2]
213	NALDLNLKTKERIVE	ubiquitination	[2]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 228 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:InterPro.
 GO:0006788; P:heme oxidation; IEA:InterPro.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0006979; P:response to oxidative stress; IEA:Compara. 

Interpro

 IPR002051; Haem_Oase.
 IPR016053; Haem_Oase-like.
 IPR016084; Haem_Oase-like_multi-hlx.
 IPR018207; Haem_oxygenase_CS. 

Pfam

 PF01126; Heme_oxygenase 

SMART

  

PROSITE

 PS00593; HEME_OXYGENASE 

PRINTS

 PR00088; HAEMOXYGNASE.