| Tag | Content |
|---|
| CPLM ID | CPLM-018061 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DDB1- and CUL4-associated factor 11 |
Protein Synonyms/Alias | WD repeat-containing protein 23 |
Gene Name | DCAF11 |
Gene Synonyms/Alias | WDR23; GL014; PRO2389 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 375 | RYLISNSKDQTIKLW | ubiquitination | [1] | | 380 | NSKDQTIKLWDIRRF | ubiquitination | [1] | | 415 | RWQQVPKKAWRKLKL | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
Sequence Annotation | REPEAT 170 210 WD 1.
REPEAT 216 258 WD 2.
REPEAT 263 302 WD 3.
REPEAT 305 345 WD 4.
REPEAT 353 392 WD 5.
REPEAT 435 480 WD 6.
REPEAT 481 520 WD 7.
MOD_RES 75 75 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Ubl conjugation pathway; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 546 AA |
Protein Sequence | MGSRNSSSAG SGSGDPSEGL PRRGAGLRRS EEEEEEDEDV DLAQVLAYLL RRGQVRLVQG 60
GGAANLQFIQ ALLDSEEEND RAWDGRLGDR YNPPVDATPD TRELEFNEIK TQVELATGQL 120
GLRRAAQKHS FPRMLHQRER GLCHRGSFSL GEQSRVISHF LPNDLGFTDS YSQKAFCGIY 180
SKDGQIFMSA CQDQTIRLYD CRYGRFRKFK SIKARDVGWS VLDVAFTPDG NHFLYSSWSD 240
YIHICNIYGE GDTHTALDLR PDERRFAVFS IAVSSDGREV LGGANDGCLY VFDREQNRRT 300
LQIESHEDDV NAVAFADISS QILFSGGDDA ICKVWDRRTM REDDPKPVGA LAGHQDGITF 360
IDSKGDARYL ISNSKDQTIK LWDIRRFSSR EGMEASRQAA TQQNWDYRWQ QVPKKAWRKL 420
KLPGDSSLMT YRGHGVLHTL IRCRFSPIHS TGQQFIYSGC STGKVVVYDL LSGHIVKKLT 480
NHKACVRDVS WHPFEEKIVS SSWDGNLRLW QYRQAEYFQD DMPESEECAS APAPVPQSST 540
PFSSPQ 546 |
Gene Ontology | GO:0080008; C:Cul4-RING ubiquitin ligase complex; IDA:UniProtKB. GO:0016567; P:protein ubiquitination; IC:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |