CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018475
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Golgin subfamily A member 4 
Protein Synonyms/Alias
 tGolgin-1 
Gene Name
 Golga4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1010TVLELSQKEKQFNAQubiquitination[1]
1952GAERDKQKLSKEVARacetylation[2]
1955RDKQKLSKEVARLQKacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1 (By similarity). 
Sequence Annotation
 DOMAIN 2178 2225 GRIP.
 REGION 154 224 Interaction with MACF1 (By similarity).
 MOD_RES 41 41 Phosphoserine.
 MOD_RES 93 93 Phosphoserine (By similarity).
 MOD_RES 100 100 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2238 AA 
Protein Sequence
MFKKLKQKIS EEQQQLQQAL APAQASSSSS TPTRTRSRTS SFTDQLDDVT PNRENASTQA 60
TKSPDGVSKD ESSPSQSGDT QTFAQKLQLR VPSMESLFRS PIKESLFRSS KEPLVRTSSR 120
ESLNQLDLDC SAAAFDPPSD MESEAEDAPW NSDGLSREQL LQRLRRMERS LSSYRGKYSE 180
LVTAFQTLQR EKKKLQGILS QSQDKSLRRI SELREELQMD QQAKKHLQDE FDACLEEKDQ 240
YISVLQTQVS LLKQRLQNGP MNVDAPKPLP PGELQAEVHG DTEKMEGVGE PVGGGTSAKT 300
LEMLQQRVKR QENLLQRCKE TIGSHKEQCA LLLSEKEALQ EQLDERLQEL EKMKELHMAE 360
KTKLITQLRD AKNLIEQLEQ DKGMVITETK RQMLETLELK EDEIAQLRSH IKQMTTQGEE 420
LREQKEKSER AAFEELEKAL STAQKTEDAQ RRMKMEMDEQ MKAVERASEE ERLRLQHELS 480
RVRQEAASMA KKNSEEQVAA LQKLHAEELA SKEQELSRRL EARERELQEQ MRIALEKSRS 540
EYLKLTQEKE QQESLALEEL ELQKKAILTE SENKLQELGQ EAEAYRTRIL ELETSLEKSL 600
QESKTQSEHL AVHLEAEKNK HNKELTALAE QHRTEVEGLQ QQQDSLWTER LQSLSQQHQA 660
AVEELREKYQ QEKDALLKEK ESLFQAHIQD MNEKTLEKLD KKQMELESVS SELSEALRAR 720
DQLAEELSVL RGDADKMKQA LEAELEEQRR HHQREVGSIS EQQELTVRRA EKALKDELSR 780
LGALLDERDE HLRERQARVQ DLEAHLQKSA GELQQALAKL DLLHSEQSAA REQAGAYEEQ 840
LAQMQQKVLD LETEKSLLTK QVVEMETHKK HVCEELDAQR AQVQQLERQR SELEEKVRSL 900
AQLQDSQLKN STVEKEQARQ SLMEKENIIL QMREEQAKEI EILKQTLSSK EESISILHEE 960
YETKFKNQEK RMEKIKQKAK EMQETKKKLL DQEAKLKKEL ENTVLELSQK EKQFNAQILE 1020
MAQANSAGIS DTVSRLEENQ RQQIESLTGA HQRKLDDVIE AWEKKLSQQA AELRDKHAEQ 1080
MEEKEQGLGE LRQKVRIVQS EKEELTKEVA RLKEAVSGQD VALAGLQGQL EQKSAVIVSL 1140
SERESQLQSQ VEKLEADLGC SLSEKLSLQE ELAELKLLAD KSQLRVSELT GQVQAAEKEL 1200
QSCKSLHELS KKSLEDKSLN LKSLLEELAS QLDSRCERTK ALLEAKTNEL VCTSRDKADA 1260
ILARLSQCQR HTATVGEALL RRMGQVSELE AQLTQLTEEQ RTLKSSFQQV TNQLEEKEKQ 1320
IKTMKADIEG LLTEKEALQQ EGGQQRQAAS EKESCITQLK KELAENINAV TLLREELSEK 1380
KSEIASLSKQ LSDLGAQLES SISPSDKAEA ISALSKQHEE QELQLQAQLQ ELSLKVDALS 1440
KEKMSALEQV DHWSNKFSEW KKKAQSRLAQ HQSTIKDLQA QLDVKATDAR EKEEQICLLK 1500
EDLDRQNKKF ECLKGEMEVR KSKMEKKECD LETALKTQTA RVVELEDCVT QRKKEVESLN 1560
ETLKNYNQQR DTEHSGLVQR LQHLEELGEE KDNKVREAEE TVLRLREHVS SLEAELGTVK 1620
KELEHVNSSV KSRDGELKAL EDKLELESAA KVELKRKAEQ KIAAIRKQLL SQMEEKTQRY 1680
AKDTENRLSE LSAQLKEREK QVHSLEDKLK NLESSPHPEV PAVSRSMQSV AASPEQEAPD 1740
SQDCTHKACK ERLCMLQRRL SEKEKLLRRL EQGEGEARPS QPEAQHRALS GKLDCTRARQ 1800
LEDHVLIGCL PEELEEKMKC SLIVSQPMGE ETGNNTGVKQ NWASVVDSVQ KTLQEKELTC 1860
QALEQRVKEL ESDLVRERGA HRLEVEKLTL KYEKSQSSQQ EMDGENKCVE VLEDRPEENS 1920
QSHEIQSNVG TVDGLRSDLE SKLTGAERDK QKLSKEVARL QKELRALRRE HQQELDILKR 1980
ECEQEAEEKL KQEQEDLELK HTSTLKQLMR EFNTQLAQKE QELERTVQET IDKAQEVEAE 2040
LLESHQEETQ QLHRKIAEKE DDLRRTARRY EEILDAREEE MTGKVTDLQT QLEELQKKYQ 2100
QRLEQEESTK DSVTILELQT QLAQKTTLIS DSKLKEQELR EQVHNLEDRL KRYEKNACAA 2160
TVGTPYKGGN LYHTEVSLFG EPTEFEYLRK VMFEYMMGRE TKTMAKVITT VLKFPDDQAQ 2220
KILEREDARL MSWLRTSS 2238 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:MGI.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.
 GO:0000042; P:protein targeting to Golgi; IEA:InterPro. 
Interpro
 IPR000237; GRIP. 
Pfam
 PF01465; GRIP 
SMART
 SM00755; Grip 
PROSITE
 PS50913; GRIP 
PRINTS