CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005928
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP synthase subunit d, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 ATP7 
Gene Synonyms/Alias
 YKL016C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
71KNTSVIDKIESYVKQacetylation[1]
77DKIESYVKQYKPVKIacetylation[1]
88PVKIDASKQLQVIESacetylation[1]
113ETESLVSKELKDLQSacetylation[1]
158EEMVKKGKWDVPGYKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. 
Sequence Annotation
 MOD_RES 2 2 N-acetylserine.  
Keyword
 Acetylation; ATP synthesis; CF(0); Complete proteome; Direct protein sequencing; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 174 AA 
Protein Sequence
MSLAKSAANK LDWAKVISSL RITGSTATQL SSFKKRNDEA RRQLLELQSQ PTEVDFSHYR 60
SVLKNTSVID KIESYVKQYK PVKIDASKQL QVIESFEKHA MTNAKETESL VSKELKDLQS 120
TLDNIQSARP FDELTVDDLT KIKPEIDAKV EEMVKKGKWD VPGYKDRFGN LNVM 174 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0000274; C:mitochondrial proton-transporting ATP synthase, stator stalk; IMP:SGD.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IDA:GOC.
 GO:0015986; P:ATP synthesis coupled proton transport; IDA:SGD.
 GO:0006461; P:protein complex assembly; IPI:SGD. 
Interpro
 IPR008689; ATPase_F0-cplx_dsu_mt. 
Pfam
 PF05873; Mt_ATP-synt_D 
SMART
  
PROSITE
  
PRINTS