CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011494
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synchronized import protein 1 
Protein Synonyms/Alias
 Symportin 1 
Gene Name
 SYO1 
Gene Synonyms/Alias
 YDL063C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
149AEQQPQLKPAGKSKIacetylation[1]
595KNKNPELKERCHDCFubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269] 
Functional Description
 Nuclear import adapter that specifically recruits the two functionally and topologically linked ribosomal proteins RPL5 and RPL11 (encoded by RPL11A and RPL11B). Guarantees that this cargo pair remains bound together from the time of synthesis in the cytoplasm until delivery to the nascent 5S rRNA in the nucleus. 
Sequence Annotation
 REPEAT 25 64 ARM 1.
 REPEAT 66 106 ARM 2.
 REPEAT 181 221 ARM 3.
 REPEAT 258 299 ARM 4.
 REPEAT 340 386 ARM 5.
 REPEAT 435 470 ARM 6.
 REPEAT 471 510 ARM 7.
 REPEAT 564 607 ARM 8.  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Protein transport; Reference proteome; Repeat; Ribosome biogenesis; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 620 AA 
Protein Sequence
MGRSKKRSRA SSSRLNPLRK AGSNDNNKDT NVVNKKLQPL LQNLSSVVPN DRSIALSSIS 60
VLCEDAHMRQ LLLKEKLVPI ILNKLLNDSN SDIVVESFGL LRNLSLEEGY DVSIYLWRSD 120
IWTSITSNFG RIVESLSALQ AAEQQPQLKP AGKSKIESKR LLFDFADNLL SLVVALSNGS 180
DDILNEILTE SKINEIFQVI SQLLKYGVEK LPINLFNTTL DLIYDLSSES FEFIDHVSNN 240
ELLSQFLNGL SPALHPQANE LTKVLIEGIH CQFLDMKITY DQCNKMIHSV CHSINNIDPV 300
QLVNDINNPV EIGPATSKDE SSKVITKIKD YNAKRNESMI KLQSIEIAID LITAIIEIVA 360
SKYESPESQE VAIPEELINT LTNFLPHVFM ILKDTFTSRI LIGWNNLIWL FVSLSLTELS 420
GELLTTLWSY VTQLDSQDDL SIKIGRMGCI WALLKLIFPD GAFESENRAL INVQMLNNSG 480
FARGIIEEFQ NNNDLELQQK CINVLSTYAM IQGQIDANKE IGQFFIQTLT QLNVRPEILI 540
EMTNSLFQIY GDASYDYNEP IFVRGGFLSI LKDQVVPNLR QQFKMVDKNK NPELKERCHD 600
CFTTLDSFIH YKMNENSTNQ 620 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0042273; P:ribosomal large subunit biogenesis; IMP:SGD. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
  
SMART
  
PROSITE
 PS50176; ARM_REPEAT 
PRINTS