CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023848
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tesmin 
Protein Synonyms/Alias
 Metallothionein-like 5, testis-specific; Testis-specific metallothionein-like protein 
Gene Name
 MTL5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40IGLKAPVKYEEDEFHacetylation[1]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861
Functional Description
 May have a role in spermatogenesis (Probable). 
Sequence Annotation
 DOMAIN 292 405 CRC.
 MOD_RES 40 40 N6-acetyllysine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Developmental protein; Differentiation; Nucleus; Polymorphism; Reference proteome; Spermatogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 508 AA 
Protein Sequence
MEEGPLPGGL PSPEDAMVTE LLSPEGPFAS ENIGLKAPVK YEEDEFHVFK EAYLGPADPK 60
EPVLHAFNPA LGADCKGQVK AKLAGGDSDG GELLGEYPGI PELSALEDVA LLQAPQPPAC 120
NVHFLSSLLP AHRSPAVLPL GAWVLEGASH PGVRMIPVEI KEAGGTTTSN NPEEATLQNL 180
LAQESCCKFP SSQELEDASC CSLKKDSNPM VICQLKGGTQ MLCIDNSRTR ELKALHLVPQ 240
YQDQNNYLQS DVPKPMTALV GRFLPASTKL NLITQQLEGA LPSVVNGSAF PSGSTLPGPP 300
KITLAGYCDC FASGDFCNNC NCNNCCNNLH HDIERFKAIK ACLGRNPEAF QPKIGKGQLG 360
NVKPQHNKGC NCRRSGCLKN YCECYEAQIM CSSICKCIGC KNYEESPERK TLMSMPNYMQ 420
TGGLEGSHYL PPTKFSGLPR FSHDRRPSSC ISWEVVEATC ACLLAQGEEA EKEHCSKCLA 480
EQMILEEFGR CLSQILHTEF KSKGLKME 508 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0046872; F:metal ion binding; NAS:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0006875; P:cellular metal ion homeostasis; NAS:UniProtKB.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0010038; P:response to metal ion; NAS:UniProtKB.
 GO:0007283; P:spermatogenesis; NAS:UniProtKB. 
Interpro
 IPR005172; CRC. 
Pfam
 PF03638; CXC 
SMART
  
PROSITE
 PS51634; CRC 
PRINTS