| Tag | Content |
|---|
| CPLM ID | CPLM-003763 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger and BTB domain-containing protein 48 |
Protein Synonyms/Alias | Krueppel-related zinc finger protein 3; Protein HKR3; Zinc finger protein 855 |
Gene Name | ZBTB48 |
Gene Synonyms/Alias | HKR3; ZNF855 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 18 | RVLQELNKQREKGQY | ubiquitination | [1] | | 560 | QICGKTFKAVEQLRV | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Binds to and regulates the J and/or S elements in MHC II promoter. |
Sequence Annotation | DOMAIN 26 89 BTB.
ZN_FING 291 313 C2H2-type 1.
ZN_FING 319 341 C2H2-type 2; degenerate.
ZN_FING 350 372 C2H2-type 3.
ZN_FING 378 401 C2H2-type 4.
ZN_FING 407 430 C2H2-type 5.
ZN_FING 436 459 C2H2-type 6.
ZN_FING 465 487 C2H2-type 7.
ZN_FING 493 515 C2H2-type 8.
ZN_FING 521 544 C2H2-type 9.
ZN_FING 550 572 C2H2-type 10.
ZN_FING 578 600 C2H2-type 11. |
Keyword | 3D-structure; Activator; Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 688 AA |
Protein Sequence | MDGSFVQHSV RVLQELNKQR EKGQYCDATL DVGGLVFKAH WSVLACCSHF FQSLYGDGSG 60
GSVVLPAGFA EIFGLLLDFF YTGHLALTSG NRDQVLLAAR ELRVPEAVEL CQSFKPKTSV 120
GQAAGGQSGL GPPASQNVNS HVKEPAGLEE EEVSRTLGLV PRDQEPRGSH SPQRPQLHSP 180
AQSEGPSSLC GKLKQALKPC PLEDKKPEDC KVPPRPLEAE GAQLQGGSNE WEVVVQVEDD 240
GDGDYMSEPE AVLTRRKSNV IRKPCAAEPA LSAGSLAAEP AENRKGTAVP VECPTCHKKF 300
LSKYYLKVHN RKHTGEKPFE CPKCGKCYFR KENLLEHEAR NCMNRSEQVF TCSVCQETFR 360
RRMELRVHMV SHTGEMPYKC SSCSQQFMQK KDLQSHMIKL HGAPKPHACP TCAKCFLSRT 420
ELQLHEAFKH RGEKLFVCEE CGHRASSRNG LQMHIKAKHR NERPHVCEFC SHAFTQKANL 480
NMHLRTHTGE KPFQCHLCGK TFRTQASLDK HNRTHTGERP FSCEFCEQRF TEKGPLLRHV 540
ASRHQEGRPH FCQICGKTFK AVEQLRVHVR RHKGVRKFEC TECGYKFTRQ AHLRRHMEIH 600
DRVENYNPRQ RKLRNLIIED EKMVVVALQP PAELEVGSAE VIVESLAQGG LASQLPGQRL 660
CAEESFTGPG VLEPSLIITA AVPEDCDT 688 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:HPA. GO:0005634; C:nucleus; IDA:HPA. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |