CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035383
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATPase, H transporting, lysosomal V1 subunit B1 (Predicted), isoform CRA_b 
Protein Synonyms/Alias
 Protein Atp6v1b1 
Gene Name
 Atp6v1b1 
Gene Synonyms/Alias
 Atp6v1b1_predicted; rCG_56434 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
208CRQAGLVKKSKAVLDacetylation[1]
483KLLRIFPKEMLKRIPacetylation[1]
487IFPKEMLKRIPQSVTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrogen ion transport; Ion transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 513 AA 
Protein Sequence
MATQVDGRPS GFTSNSCDPG TAREHVQVVT RNYITHPRVT YRTVCSVNGP LVVLDQVKFA 60
QYAEIVNFTL PDGTQRSGQV LEVAGTKAIV QVFEGTSGID SQKTTCEFTG DILRTPVSED 120
MLGRIFNGSG KPIDKGPAVM AEDFLDINGQ PINPHDRIYP EEMIQTGISP IDVMNSIARG 180
QKIPIFSAAG LPHNEIAAQI CRQAGLVKKS KAVLDYHEDN FAIVFAAMGV NMETARFFKS 240
DFEQNGTMGN VCLFLNLAND PTIERIITPR LALTTAEFLA YQCEKHVLVI LTDMSSYAEA 300
LREVSAAREE VPGRRGFPGY MYTDLATIYE RAGRVEGRGG SITQIPILTM PNDDITHPIP 360
DLTGFITEGQ IYVDRQLHNR QVYPPINVLP SLSRLMKSAI GEGMTRKDHG DVSNQLYACY 420
AIGKDVQAMK AVVGEEALTS EDLLYLEFLQ KFEKNFINQG PYENRTVFES LDLGWKLLRI 480
FPKEMLKRIP QSVTDEFYSR QGAQQDPASD TAL 513 
Gene Ontology
 GO:0016324; C:apical plasma membrane; ISS:UniProtKB.
 GO:0016323; C:basolateral plasma membrane; IDA:RGD.
 GO:0005829; C:cytosol; ISS:UniProtKB.
 GO:0016328; C:lateral plasma membrane; ISS:UniProtKB.
 GO:0005902; C:microvillus; ISS:UniProtKB.
 GO:0033180; C:proton-transporting V-type ATPase, V1 domain; IEA:InterPro.
 GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; ISS:UniProtKB.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; ISS:UniProtKB.
 GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0046034; P:ATP metabolic process; IEA:InterPro.
 GO:0055074; P:calcium ion homeostasis; ISS:UniProtKB.
 GO:0007588; P:excretion; ISS:UniProtKB.
 GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
 GO:0001503; P:ossification; ISS:UniProtKB.
 GO:0045851; P:pH reduction; ISS:UniProtKB.
 GO:0007605; P:sensory perception of sound; ISS:UniProtKB. 
Interpro
 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR005723; ATPase_V1-cplx_bsu.
 IPR027417; P-loop_NTPase.
 IPR022879; V-ATPase_su_B/beta. 
Pfam
 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 
SMART
  
PROSITE
 PS00152; ATPASE_ALPHA_BETA 
PRINTS