UniProt Accession

 DIRA2_MOUSE; Q5PR73 

Genbank Protein ID

 BC086799 

Genbank Nucleotide ID

 AAH86799.1 

Protein Name

 GTP-binding protein Di-Ras2 

Protein Synonyms/Alias

 Distinct subgroup of the Ras family member 2 

Gene Name

 Diras2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
170	QELLNLEKRRTVSLQ	ubiquitination	[1]
181	VSLQIDGKKSKQQKR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Displays low GTPase activity and exist predominantly in the GTP-bound form (By similarity). 

Sequence Annotation

 NP_BIND 14 21 GTP (By similarity).
 NP_BIND 33 39 GTP (By similarity).
 NP_BIND 61 65 GTP (By similarity).
 NP_BIND 121 124 GTP (By similarity).
 MOTIF 36 44 Effector region (Potential).
 MOD_RES 196 196 Cysteine methyl ester (Potential).
 LIPID 196 196 S-geranylgeranyl cysteine (By  

Keyword

 Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 199 AA 

Protein Sequence

Gene Ontology

 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR020849; Small_GTPase_Ras. 

Pfam

 PF00071; Ras 

SMART

 SM00173; RAS 

PROSITE

 PS51421; RAS 

PRINTS

 PR00449; RASTRNSFRMNG.