| Tag | Content |
|---|
| CPLM ID | CPLM-011015 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glycerophosphodiester phosphodiesterase GDE1 |
Protein Synonyms/Alias | |
Gene Name | GDE1 |
Gene Synonyms/Alias | YPL110C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 213 | NQQMSTMKTRILPLQ | ubiquitination | [1] | | 794 | HNRIDCQKNNNNYVM | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline. The choline is used for phosphatidyl-choline synthesis. Required for utilization of glycerophosphocholine as phosphate source. |
Sequence Annotation | DOMAIN 1 213 SPX.
REPEAT 427 456 ANK 1.
REPEAT 472 502 ANK 2.
REPEAT 504 533 ANK 3.
REPEAT 538 567 ANK 4.
REPEAT 572 601 ANK 5.
REPEAT 605 634 ANK 6.
DOMAIN 877 1212 GDPD.
MOD_RES 653 653 Phosphoserine.
MOD_RES 983 983 Phosphoserine. |
Keyword | ANK repeat; Complete proteome; Cytoplasm; Hydrolase; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1223 AA |
Protein Sequence | MKFGKTFANH RIPEWSSQYV GYKSLKKMIK EITRLQEDIY RAHNKNSYDE GRPPTKMRDS 60
SNSAQNYLDS PKIQKLLASF FFAVDRDIEK VDTFYNSQYA EYKKRFERLL SSNQFNEIKS 120
TLVVDANKED AVAQTLLTKD TREMNMLLKG TSQASRLSYH KDDLIEIQSI LAELRKQFRN 180
LKWYAELNKR AFGKILKKLD KKVGTNQQMS TMKTRILPLQ FANDSLITKD LSLLKTIWEQ 240
VTFRINSYER VMRSTSPNAN ANDNTEFFKI ICVFIEEDDS KGLIRELTNL YSELSLIPTR 300
IMISVLNKAA LSKSLACIDA ILKVIPSLND SEDINRRNFF HHHIIAIGKL IRKQEILSRK 360
KKSQPSKYTN SEGEIVTDLR TLHTTLSAPA ESDSITEEEK SSACTLSYIL EELPIHLRPC 420
LFQHDNYKRT PLHYSCQYGL SEVTKLIIKL MKEWNIWNEI PIDDVSAFGD AESLTPLHLC 480
VLGAHPKTTE VLLQSLDPNV KLKSSSLLHL ATEWNNYPLL HVLLSSKRFD INYQDNELHE 540
TPLYLACRLN FFEAAVCLLY NGADLEIREK LFGWTAIFVA AAEGFTDIVK LLIANNANFD 600
IEDEGGWTPM EHAVLRGHLH IADMVQIRDE LVTHPHSQLN SGSEEKEPLN EISAGELNER 660
NENGNGGNKG SLGKLAGPIK SYGHRFLDNN ESLILITLGS NDTRNKSPSI SLSSEALAKV 720
IGLETDCALS LVISCNDSID KSSVILDLPL DDNVDAVDFK VPFKVDYSHT LYFDIVPTYG 780
TRSLETHNRI DCQKNNNNYV MARGVSMLNK SYSSVGVNRS ILNGSVTVPI IANHTLEILG 840
TLKFEYIIIT PFEHPQLPLE RTETYWKSLV STRVIGHRGL GKNNPNKSLQ IGENTVESFI 900
MAASLGASYV EFDVQLTKDN VPVVYHDFLV AETGVDIPMH ELTLEQFLDL NNADKEHIQR 960
GAGHSPHHVN GADTALQKYR GRSVDDSDVS TLRRAWDLHD NDPNGKSNNA HWSDNRMRLT 1020
KTFKKNNFKG NARGHSIASS FVTLKELFKK IPANVGFNIE CKFPMLDEAE EEELGQIMME 1080
MNHWVDTVLK VVFDNANGRD IIFSSFHPDI CIMLSLKQPV IPILFLTEGG SEQMADLRAS 1140
SLQNGIRFAK KWNLLGIVSA AAPILKAPRL VQVVKSNGLV CVTYGVDNND PENASIQIEA 1200
GVDAVIVDSV LAIRRGLTKK NEK 1223 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IMP:SGD. GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:EC. GO:0006071; P:glycerol metabolic process; IEA:InterPro. GO:0046475; P:glycerophospholipid catabolic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |