CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034845
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Wwox 
Protein Synonyms/Alias
  
Gene Name
 Wwox 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
174RILEEWHKAKVEAMTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP 60
YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR 120
DFTGKVVLVT GANSGIGFET AKSFALHGAH VILACRNMSR ASEAVSRILE EWHKAKVEAM 180
TLDLAVLRSV QHFAEAFKAK NVPLHILVCN AGTFALPWSL TKDGLETTFQ VNHLGHFYLV 240
QLLQDVLCRS APARVIVVSS ESHRFTDIND SSGKLDLSRL SLSSSDYWAM LAYNRSKLCN 300
ILFSNELHRL LSPRGVTSNA LHPGNMMFSA IHRNSWVYKL LFTLARPFTK SMVNKP 356 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005902; C:microvillus; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Compara.
 GO:0006917; P:induction of apoptosis; IEA:Compara.
 GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IEA:Compara.
 GO:0001649; P:osteoblast differentiation; IEA:Compara.
 GO:0055114; P:oxidation-reduction process; IEA:GOC.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0048705; P:skeletal system morphogenesis; IEA:Compara. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR001202; WW_dom. 
Pfam
 PF00106; adh_short
 PF00397; WW 
SMART
 SM00456; WW 
PROSITE
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 
PRINTS
 PR00081; GDHRDH.