UniProt Accession

 GBG4_MOUSE; P50153 

Genbank Protein ID

 U37527; AF038594; AF038593; BC016506 

Genbank Nucleotide ID

 AAB93460.1; AAC40090.1; AAC40090.1; AAH16506.1 

Protein Name

 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 

Protein Synonyms/Alias

  

Gene Name

 Gng4 

Gene Synonyms/Alias

 Gngt4 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
24	RKAVEQLKMEACMDR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. 

Sequence Annotation

 MOD_RES 72 72 Cysteine methyl ester (By similarity).
 LIPID 72 72 S-geranylgeranyl cysteine (By  

Keyword

 Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Prenylation; Reference proteome; Transducer. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 75 AA 

Protein Sequence

Gene Ontology

 GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI.
 GO:0003924; F:GTPase activity; ISA:MGI.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI.
 GO:0030308; P:negative regulation of cell growth; IEA:Compara. 

Interpro

 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 

Pfam

 PF00631; G-gamma 

SMART

 SM00224; GGL 

PROSITE

 PS50058; G_PROTEIN_GAMMA 

PRINTS

 PR00321; GPROTEING.