CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031243
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Angiopoietin-1 
Protein Synonyms/Alias
 cDNA FLJ56604, highly similar to Angiopoietin-1 
Gene Name
 ANGPT1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
198RFHIGNEKQNYRLYLubiquitination[1]
228HGADFSTKDADNDNCubiquitination[1]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
MEGKHKEELD TLKEEKENLQ GLVTRQTYII QELEKQLNRA TTNNSVLQKQ QLELMDTVHN 60
LVNLCTKEGV LLKGGKREEE KPFRDCADVY QAGFNKSGIY TIYINNMPEP KKVFCNMDVN 120
GGGWTVIQHR EDGSLDFQRG WKEYKMGFGN PSGEYWLGNE FIFAITSQRQ YMLRIELMDW 180
EGNRAYSQYD RFHIGNEKQN YRLYLKGHTG TAGKQSSLIL HGADFSTKDA DNDNCMCKCA 240
LMLTGGWWFD ACGPSNLNGM FYTAGQNHGK LNGIKWHYFK GPSYSLRSTT MMIRPLDF 298 
Gene Ontology
 GO:0001525; P:angiogenesis; IEA:Compara.
 GO:0031589; P:cell-substrate adhesion; IEA:Compara.
 GO:0072012; P:glomerulus vasculature development; IEA:Compara.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0043116; P:negative regulation of vascular permeability; IEA:Compara.
 GO:0045785; P:positive regulation of cell adhesion; IEA:Compara.
 GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Compara.
 GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Compara.
 GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IEA:Compara.
 GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Compara. 
Interpro
 IPR014716; Fibrinogen_a/b/g_C_1.
 IPR014715; Fibrinogen_a/b/g_C_2.
 IPR002181; Fibrinogen_a/b/g_C_dom.
 IPR020837; Fibrinogen_CS. 
Pfam
 PF00147; Fibrinogen_C 
SMART
 SM00186; FBG 
PROSITE
 PS00514; FIBRINOGEN_C_1
 PS51406; FIBRINOGEN_C_2 
PRINTS